{"id":"W2106986485","doi":"10.1016/j.biotechadv.2014.04.003","title":"Technical guide for genetic advancement of underdeveloped and intractable Clostridium","year":2014,"lang":"en","type":"review","venue":"Biotechnology Advances","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centurion Biofuels (Canada); University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Blueprint; Biology; Biotechnology; Clostridia; Metagenomics; Computational biology; Genetics; Gene; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006409095,0.001490782,0.001055203,0.003985269,0.0003227311,0.001041139,0.0007808647,0.001212503,0.01807041],"category_scores_gemma":[0.001032343,0.0004915792,0.0005091407,0.002579937,0.0005175721,0.00155071,0.001012325,0.002524383,0.01639164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006234872,"about_ca_system_score_gemma":0.002257626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001543663,"about_ca_topic_score_gemma":0.004089742,"domain_scores_codex":[0.9997261,0.00003462897,0.00003877617,0.00003524622,0.0001387749,0.00002655186],"domain_scores_gemma":[0.9995921,0.0001382412,0.00007228162,0.00002101324,0.0001229222,0.00005338045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004458128,0.00007097174,0.00005395457,0.008002117,0.00001986859,0.0001994718,0.00004055542,0.000190611,0.007009534,0.006081003,0.2667997,0.7114877],"study_design_scores_gemma":[0.000009880529,0.00003732915,0.0001041878,0.0008237392,0.00001317885,0.0002829214,0.000009270089,0.00002861729,0.000531351,0.0009791091,0.9971725,0.000007977063],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002635867,0.9572964,0.00612834,0.002751964,0.00385385,0.0001615703,0.0009704362,0.0003429573,0.02823091],"genre_scores_gemma":[0.0009457615,0.9523376,0.007155021,0.002286889,0.0009064092,0.0001439489,0.0009257033,0.00005005302,0.03524856],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01807041,"threshold_uncertainty_score":0.06045151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03895556488062202,"score_gpt":0.3809136347470324,"score_spread":0.3419580698664104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}