{"id":"W2106994186","doi":"10.1084/jem.193.1.61","title":"A Regulatory Role for Src Homology 2 Domain–Containing Inositol 5′-Phosphatase (Ship) in Phagocytosis Mediated by Fcγ Receptors and Complement Receptor 3 (α<b>M</b>β<b>2</b>; Cd11b/Cd18)","year":2000,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; American Heart Association","keywords":"Phagocytosis; Cell biology; Integrin alpha M; Receptor; Biology; Complement receptor; Proto-oncogene tyrosine-protein kinase Src; Phagosome; Inositol; Signal transduction; Biochemistry; Immunology; Complement system; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001546944,0.0003062658,0.0008383015,0.0002266285,0.0002015147,0.00001129544,0.0002833614,0.0001127017,0.0040242],"category_scores_gemma":[0.0001263929,0.0001877311,0.000111269,0.0002545976,0.0006870536,0.0001271937,0.00007314897,0.0004899562,0.00001605049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002494144,"about_ca_system_score_gemma":0.0001086334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004220681,"about_ca_topic_score_gemma":0.00001788213,"domain_scores_codex":[0.9972043,0.0002846556,0.001006147,0.0002452976,0.0007185082,0.0005410859],"domain_scores_gemma":[0.9981847,0.0007208965,0.0003038721,0.0002286872,0.0001264203,0.0004353623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.03565211,0.001264871,0.01443449,0.0001424057,0.0006023305,0.0002027125,0.01582357,0.000003744729,0.7831013,0.0005727907,0.1243743,0.02382547],"study_design_scores_gemma":[0.03810803,0.02795624,0.005160977,0.001771337,0.000359702,0.003594989,0.0323451,0.0002675218,0.4166384,0.0004704244,0.4726031,0.0007241789],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9494698,0.03900127,0.00001108121,0.009824572,0.0002631318,0.0007430719,0.00005191628,0.00001217339,0.0006229628],"genre_scores_gemma":[0.993384,0.002339392,0.0007959261,0.00189226,0.0006351182,0.00004311652,0.0001202842,0.00003951715,0.0007504097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3664629,"threshold_uncertainty_score":0.9968863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02277070121986929,"score_gpt":0.3270052833970561,"score_spread":0.3042345821771868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}