{"id":"W2107088171","doi":"10.1128/mcb.20.12.4199-4209.2000","title":"Two Regulators of Ste12p Inhibit Pheromone-Responsive Transcription by Separate Mechanisms","year":2000,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Saccharomyces cerevisiae; Transcription factor; Fusion protein; Transcription (linguistics); Promoter; Gene; Molecular biology; Repressor lexA; Biochemistry; Cell biology; Genetics; Recombinant DNA; Gene expression; Repressor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002295104,0.0008393076,0.0006483117,0.0003742736,0.0002078766,0.000664815,0.0005657657,0.0004475308,0.002958558],"category_scores_gemma":[0.0002799771,0.0004990536,0.000638655,0.0001978964,0.000347612,0.0003758866,0.0009602101,0.001052697,0.001362475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006197559,"about_ca_system_score_gemma":0.0003377084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002687866,"about_ca_topic_score_gemma":0.0006755212,"domain_scores_codex":[0.9993979,0.00006116447,0.00005073809,0.0001094484,0.0002333144,0.000147438],"domain_scores_gemma":[0.9996087,0.00008524271,0.00008290421,0.00005698721,0.00007037002,0.00009571153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001895068,0.00004310223,0.0001438956,0.00003485044,0.000006038405,0.00003247826,0.00001129522,0.0000454168,0.9978504,0.0001583691,0.00005593697,0.001428649],"study_design_scores_gemma":[0.00002805836,0.000117809,0.002921066,0.000005595158,0.000009863818,0.0001324352,0.00001504859,0.0006169939,0.9940241,0.00005833526,0.002065547,0.000005161186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9706057,0.008545573,0.009409832,0.0003132597,0.0001522504,0.0001161603,0.0006995057,0.0006386386,0.0095192],"genre_scores_gemma":[0.981915,0.002322182,0.003403955,0.0001804971,0.00004908017,0.0002493491,0.001401002,0.0001278886,0.0103512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002958558,"threshold_uncertainty_score":0.009897411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005252645095624253,"score_gpt":0.2416200369391455,"score_spread":0.2363673918435213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}