{"id":"W2107097973","doi":"10.1002/chem.201102109","title":"Probing the Intestinal α‐Glucosidase Enzyme Specificities of Starch‐Digesting Maltase‐Glucoamylase and Sucrase‐Isomaltase: Synthesis and Inhibitory Properties of 3′‐ and 5′‐Maltose‐Extended De‐<i>O</i>‐sulfonated Ponkoranol","year":2011,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo; Simon Fraser University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Maltose; Chemistry; Maltase; Sucrase; Hydrolysis; Biochemistry; Enzyme; Disaccharide; Sulfonium; Glycoside hydrolase; Starch; Alpha-glucosidase; Stereochemistry; Organic chemistry; Salt (chemistry)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001652086,0.0003688807,0.0001581289,0.0001136117,0.00005267256,0.0001405625,0.0001574757,0.0002149748,0.000596933],"category_scores_gemma":[0.0001787188,0.0001516113,0.0001445248,0.00008528907,0.0001717076,0.0001548807,0.00009817717,0.0002993297,0.0002134776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002223899,"about_ca_system_score_gemma":0.0001543588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002693594,"about_ca_topic_score_gemma":0.0003386973,"domain_scores_codex":[0.9999193,0.00002563033,0.000005089144,0.00001443506,0.00001773215,0.000017793],"domain_scores_gemma":[0.9999131,0.00002205772,0.00002765848,0.000007145029,0.00001125538,0.00001881512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009601678,0.00001603463,0.00008414553,0.0000229739,0.000002419215,0.00002200932,0.000005662233,0.00008355323,0.9981445,0.00003738585,0.000005053192,0.00148032],"study_design_scores_gemma":[0.00001896714,0.0006825178,0.001334607,0.000002303728,0.000008622013,0.0002442056,0.000005355951,0.0002782338,0.9963105,0.00001834939,0.001094143,0.000002077487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929175,0.001987134,0.003651654,0.00004547424,0.000006863345,0.00004865214,0.0001055935,0.00002922539,0.001207943],"genre_scores_gemma":[0.9921792,0.001759578,0.00434919,0.00002988908,0.000007105428,0.00003731364,0.0003436583,0.000009684785,0.001284395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000596933,"threshold_uncertainty_score":0.001996994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02522146225761657,"score_gpt":0.2111647946682136,"score_spread":0.1859433324105971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}