{"id":"W2107097973","doi":"10.1002/chem.201102109","title":"Probing the Intestinal α‐Glucosidase Enzyme Specificities of Starch‐Digesting Maltase‐Glucoamylase and Sucrase‐Isomaltase: Synthesis and Inhibitory Properties of 3′‐ and 5′‐Maltose‐Extended De‐<i>O</i>‐sulfonated Ponkoranol","year":2011,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo; Simon Fraser University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Maltose; Chemistry; Maltase; Sucrase; Hydrolysis; Biochemistry; Enzyme; Disaccharide; Sulfonium; Glycoside hydrolase; Starch; Alpha-glucosidase; Stereochemistry; Organic chemistry; Salt (chemistry)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001207852,0.0002631348,0.0002939275,0.00005141507,0.0002644158,0.00004622771,0.0001932096,0.00008478708,0.00001580223],"category_scores_gemma":[0.0004745063,0.000187135,0.00006089339,0.00008007899,0.000793441,0.00001820036,0.0001952875,0.0003712266,4.984042e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001726362,"about_ca_system_score_gemma":0.0002110139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002253541,"about_ca_topic_score_gemma":0.000001387942,"domain_scores_codex":[0.9981661,0.0003950556,0.0006145357,0.0003181589,0.0001638591,0.0003423359],"domain_scores_gemma":[0.998787,0.00006085164,0.0004825458,0.0002218448,0.0002069041,0.0002408961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004669501,0.00009325637,0.002924979,0.0007996846,0.00008787255,0.0001180766,0.001153807,0.000004773365,0.9915754,0.0000111279,0.00006528539,0.002698784],"study_design_scores_gemma":[0.0007268653,0.0003878236,0.005429649,0.001318964,0.00008054635,0.002817697,0.002612639,0.00009602361,0.9860534,0.00001410512,0.0002267295,0.000235563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914095,0.006998498,0.00006207869,0.00005679273,0.00003049147,0.0001701772,0.00003673649,0.00001256027,0.001223205],"genre_scores_gemma":[0.9982675,0.0009013345,0.0004718846,0.0000308618,0.000152931,0.000005269596,0.00000687905,0.0000427715,0.0001205462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006858062,"threshold_uncertainty_score":0.7631142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02522146225761657,"score_gpt":0.2111647946682136,"score_spread":0.1859433324105971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}