{"id":"W2107270081","doi":"10.1056/nejmoa1201546","title":"Intermittent Androgen Suppression for Rising PSA Level after Radiotherapy","year":2012,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":497,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Université de Montréal; Centre Hospitalier Universitaire de Sherbrooke; University of British Columbia; University of Toronto; Institute of Cancer Research; Juravinski Cancer Centre; Ottawa Regional Cancer Foundation; Queen's University; London Health Sciences Centre; Princess Margaret Cancer Centre; BC Cancer Agency","funders":"National Cancer Institute; Cancer Research UK","keywords":"Medicine; Androgen deprivation therapy; Prostate cancer; Hazard ratio; Clinical endpoint; Radiation therapy; Adverse effect; Urology; Randomized controlled trial; Quality of life (healthcare); Internal medicine; Testosterone (patch); Confidence interval; Surgery; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005208917,0.0001414372,0.000448641,0.0001215178,0.00003144913,0.000006388816,0.00005257547,0.00004870697,0.0002790429],"category_scores_gemma":[0.0001183419,0.00007754781,0.0001176672,0.00005687539,0.00004231658,0.0001213163,0.000009296748,0.0001425079,0.000001383532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000133376,"about_ca_system_score_gemma":0.00009868136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001721893,"about_ca_topic_score_gemma":0.000003405318,"domain_scores_codex":[0.9989537,0.00003346261,0.000402441,0.00008945302,0.0002752003,0.0002457353],"domain_scores_gemma":[0.9989281,0.0001772523,0.0002115722,0.0001249739,0.0001258211,0.000432284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005111818,0.0003443144,0.2157748,0.0001249532,0.0004716024,0.0001512345,0.003524116,0.000002803405,0.005803274,0.00002444493,0.04784308,0.7208235],"study_design_scores_gemma":[0.1599427,0.007824776,0.2085233,0.003679885,0.001114029,0.003751262,0.000282684,0.00003694837,0.01826868,0.0002680903,0.5960882,0.0002193897],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9251091,0.04926933,0.006664317,0.0164782,0.001875039,0.0004141562,0.00001259412,0.000009953657,0.0001673194],"genre_scores_gemma":[0.9838511,0.003122985,0.003388482,0.001374052,0.007915223,0.00001096725,0.000008473198,0.00002264731,0.0003060185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7206041,"threshold_uncertainty_score":0.3162308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04577815282071631,"score_gpt":0.3312288881623858,"score_spread":0.2854507353416695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}