{"id":"W2107295431","doi":"10.1155/2012/504918","title":"PPAR Medicines and Human Disease: The ABCs of It All","year":2012,"lang":"en","type":"article","venue":"PPAR Research","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Peroxisome proliferator-activated receptor; ATP-binding cassette transporter; Transporter; Transcription factor; Peroxisome; Receptor; Disease; Nuclear receptor; Pharmacology; Computational biology; Cancer; Lipid metabolism; Bioinformatics; Biology; Cancer research; Medicine; Gene; Biochemistry; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009871334,0.00009007861,0.0001005241,0.00005139215,0.0001390792,0.00001386648,0.0002412357,0.00007783136,0.000084589],"category_scores_gemma":[0.0002923014,0.00005862208,0.00003295533,0.0001141573,0.0004166936,0.000005473894,0.0002439213,0.0001869833,0.00001296968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001011983,"about_ca_system_score_gemma":0.00004988978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004222548,"about_ca_topic_score_gemma":0.00001064899,"domain_scores_codex":[0.9987374,0.0002153786,0.0001337929,0.0001836874,0.0003440038,0.0003857246],"domain_scores_gemma":[0.9992232,0.0000450898,0.00003138581,0.0003576749,0.0001260066,0.0002166671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000669789,0.00008013746,0.04808775,0.00004256938,0.00005484387,6.947162e-7,0.0001635283,5.437465e-7,0.9268241,0.0002144259,0.02404767,0.0004167859],"study_design_scores_gemma":[0.0002596261,0.0001365134,0.008821902,0.00001882712,0.00001204459,0.000003796375,0.000208461,0.000004771885,0.7450547,0.00009846099,0.2452875,0.0000934516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911532,0.004922878,0.000007389011,0.001841555,0.0000581118,0.0002032274,0.00000986842,0.00000525062,0.001798469],"genre_scores_gemma":[0.9980527,0.0006130284,0.00002311218,0.0001509529,0.0004204974,0.00003564429,0.00003443669,0.00001727039,0.0006523164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2212398,"threshold_uncertainty_score":0.2390539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07904870914967853,"score_gpt":0.4135016428695834,"score_spread":0.3344529337199049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}