{"id":"W2107295783","doi":"10.1016/j.ygeno.2004.02.012","title":"Genomic structure, promoter activity, and developmental expression of the mouse homologue of the Machado–Joseph disease (MJD) gene☆","year":2004,"lang":"en","type":"article","venue":"Genomics","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Notre-Dame","funders":"Fundação para a Ciência e a Tecnologia; Canadian Institutes of Health Research","keywords":"Biology; MyoD; Genetics; Machado–Joseph disease; Gene; Transcription factor; TATA box; Trinucleotide repeat expansion; Molecular biology; Promoter; Gene expression; Cell biology; Allele","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004162242,0.0001820841,0.0001562821,0.0000360968,0.000189543,0.0000208673,0.0005195271,0.00004370354,0.00001388619],"category_scores_gemma":[0.0001270661,0.0001141366,0.00008743186,0.0001139823,0.0003855227,0.00005208435,0.0006895924,0.0001185012,0.000002011501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007927336,"about_ca_system_score_gemma":0.0002962505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001416547,"about_ca_topic_score_gemma":0.00001558888,"domain_scores_codex":[0.9988303,0.0001500482,0.0002098655,0.0003817466,0.0002225355,0.0002055337],"domain_scores_gemma":[0.9991869,0.00003909599,0.0001905189,0.0004630331,0.00002541997,0.00009506253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005026316,0.00007538805,0.006428419,0.00002428855,0.000003569475,0.000002370363,0.0004004229,0.001571715,0.9911346,0.00007997151,0.000009919186,0.0002190306],"study_design_scores_gemma":[0.0003441993,0.00001686037,0.1896903,0.000008620728,0.0000170957,0.00001130087,0.00001609378,0.00002329209,0.8087921,0.0009555864,0.00002652471,0.00009810622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985285,0.00006119424,0.00005087526,0.0001290709,0.0001564983,0.0005699679,0.00047328,0.00001010455,0.00002050173],"genre_scores_gemma":[0.9990175,0.00002780518,0.0005877339,0.0002511573,0.00002784649,0.00001044328,0.000002242235,0.00002712829,0.00004815622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1832619,"threshold_uncertainty_score":0.4654355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01851200667199846,"score_gpt":0.2237837359148228,"score_spread":0.2052717292428244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}