{"id":"W2107295783","doi":"10.1016/j.ygeno.2004.02.012","title":"Genomic structure, promoter activity, and developmental expression of the mouse homologue of the Machado–Joseph disease (MJD) gene☆","year":2004,"lang":"en","type":"article","venue":"Genomics","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Notre-Dame","funders":"Fundação para a Ciência e a Tecnologia; Canadian Institutes of Health Research","keywords":"Biology; MyoD; Genetics; Machado–Joseph disease; Gene; Transcription factor; TATA box; Trinucleotide repeat expansion; Molecular biology; Promoter; Gene expression; Cell biology; Allele","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001066457,0.0001554173,0.0001504312,0.0004661093,0.0001716264,0.0003467906,0.0002053921,0.0002368194,0.000720748],"category_scores_gemma":[0.0001638797,0.000252644,0.0002085665,0.0001911406,0.0003355274,0.0001469668,0.0002192032,0.0006155886,0.0003142198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000333404,"about_ca_system_score_gemma":0.0001641519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00101122,"about_ca_topic_score_gemma":0.002346632,"domain_scores_codex":[0.9998672,0.00001314077,0.00001045087,0.00005061902,0.00002994365,0.00002861734],"domain_scores_gemma":[0.9998192,0.00004374168,0.00006796049,0.00001747285,0.00001192732,0.00003968549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008116549,0.00001659601,0.0005176968,0.00001060129,0.00000292696,0.00004646297,0.00003465426,0.0000456623,0.9980226,0.0002858557,0.00001770005,0.000918128],"study_design_scores_gemma":[0.0000542283,0.0003382291,0.1173953,0.0000254905,0.00008382664,0.001283285,0.0001634885,0.001648072,0.8709879,0.0007965988,0.007199049,0.00002459751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967362,0.0007465453,0.001420095,0.00006129783,0.000005708376,0.00000545198,0.0003083214,0.00002627674,0.0006900552],"genre_scores_gemma":[0.99483,0.0003941132,0.001497866,0.00004444315,0.000006380571,0.00001153498,0.001341649,0.0000330195,0.001841035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00101122,"threshold_uncertainty_score":0.002418995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01851200667199846,"score_gpt":0.2237837359148228,"score_spread":0.2052717292428244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}