{"id":"W2107346812","doi":"10.1056/nejmoa050085","title":"Costimulation Blockade with Belatacept in Renal Transplantation","year":2005,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":856,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital; University of Alberta","funders":"","keywords":"Belatacept; Medicine; Calcineurin; Immunosuppression; Blockade; Transplantation; Urology; Adverse effect; Kidney transplantation; Intensive care medicine; Pharmacology; Internal medicine; Receptor; Kidney transplant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002531504,0.0001121077,0.0003162245,0.0002534796,0.00002062021,0.000004098259,0.00003753752,0.00004249925,0.0001919338],"category_scores_gemma":[0.00002318617,0.0000634689,0.00003719547,0.0001729578,0.00003227952,0.0001382039,0.000001015376,0.0002108626,0.000004539461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005765307,"about_ca_system_score_gemma":0.00009062056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004986535,"about_ca_topic_score_gemma":0.0001457723,"domain_scores_codex":[0.9989101,0.00003567391,0.0004431995,0.00008593025,0.0004046682,0.0001203694],"domain_scores_gemma":[0.9993731,0.0001207695,0.0001754693,0.00006655064,0.00008507966,0.0001790274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02372865,0.0004861314,0.5178688,0.0002785821,0.0005061062,0.004078827,0.008652212,0.01573968,0.01099119,0.0002387756,0.0004240632,0.417007],"study_design_scores_gemma":[0.3322596,0.005190821,0.628328,0.004406311,0.001069152,0.01308736,0.0001235096,0.0007039697,0.003995216,0.0001549494,0.01050442,0.0001766783],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798979,0.0006128555,0.006301032,0.01122391,0.00009650446,0.000183192,0.00000265387,0.000009512528,0.001672477],"genre_scores_gemma":[0.9932538,0.0006878728,0.004140178,0.0003149562,0.001169279,7.151521e-7,0.00003246011,0.00001055136,0.0003901314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4168303,"threshold_uncertainty_score":0.2588187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01706769157140701,"score_gpt":0.2922987444951451,"score_spread":0.2752310529237381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}