{"id":"W2107371854","doi":"10.1128/iai.01187-15","title":"New Role of Nod Proteins in Regulation of Intestinal Goblet Cell Response in the Context of Innate Host Defense in an Enteric Parasite Infection","year":2015,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McMaster University; Population Health Research Institute","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research; McMaster University; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Wellcome Trust","keywords":"Biology; Nod; NOD1; Mucin; Goblet cell; Innate immune system; Innate lymphoid cell; NOD2; Immunology; Mucin 2; Microbiology; Immune system; Epithelium; Gene expression; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002145743,0.0003454126,0.0003441871,0.0002326411,0.0001216133,0.000356807,0.0001775676,0.0004061488,0.0006773879],"category_scores_gemma":[0.0000926041,0.0001208159,0.0002947348,0.0001041104,0.0003340623,0.0005290691,0.0003061742,0.0005198115,0.0001337216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001443238,"about_ca_system_score_gemma":0.0000972202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007933291,"about_ca_topic_score_gemma":0.0001311996,"domain_scores_codex":[0.9998704,0.0000303527,0.00001355076,0.00003371177,0.00002253516,0.00002940059],"domain_scores_gemma":[0.9998969,0.00001059796,0.00002220513,0.000007853852,0.00001546335,0.00004703813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005395836,0.00005321437,0.001243507,0.000231173,0.00001249422,0.001124619,0.00005117176,0.00007248143,0.9923587,0.0003698014,0.00007719119,0.003866007],"study_design_scores_gemma":[0.0004340195,0.004279962,0.1682032,0.0002611582,0.000328044,0.01106367,0.001123604,0.007013309,0.7714023,0.003713933,0.03207998,0.00009689078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9614007,0.02983785,0.004980921,0.0006532201,0.0001401703,0.00004379504,0.000198676,0.00008776304,0.002656878],"genre_scores_gemma":[0.9845715,0.008396368,0.003436355,0.0003175772,0.0001117343,0.00005365993,0.0002310811,0.00001289121,0.002868913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006773879,"threshold_uncertainty_score":0.002266049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01883763808530929,"score_gpt":0.2692175817742674,"score_spread":0.2503799436889581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}