{"id":"W2107385980","doi":"10.2337/diacare.29.01.06.dc05-1447","title":"Long-Term Effects of Ranirestat (AS-3201) on Peripheral Nerve Function in Patients With Diabetic Sensorimotor Polyneuropathy","year":2006,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Mylan","keywords":"Medicine; Placebo; Sural nerve; Nerve conduction velocity; Polyneuropathy; Peripheral neuropathy; Diabetic neuropathy; Biopsy; Sensory nerve; Nerve biopsy; Aldose reductase inhibitor; Nerve conduction study; Anesthesia; Diabetes mellitus; Surgery; Internal medicine; Sensory system; Nerve conduction; Endocrinology; Aldose reductase; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003003005,0.0002205147,0.0003400566,0.0001228252,0.00003617672,0.00001060982,0.00004268164,0.0000734004,0.00001835801],"category_scores_gemma":[0.00002727716,0.0001667708,0.00007877342,0.0001512045,0.00003334872,0.00005385176,0.00001431571,0.0001097328,0.00003092448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001177102,"about_ca_system_score_gemma":0.00002522829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003924576,"about_ca_topic_score_gemma":0.00001088389,"domain_scores_codex":[0.9988359,0.00007867321,0.0001827392,0.0002889371,0.0003062637,0.0003075516],"domain_scores_gemma":[0.9994109,0.00006735332,0.00008303484,0.0002623055,0.00009637295,0.0000800335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003608541,0.0005257598,0.9914911,0.0004249925,0.00004192316,0.0001010306,0.0001199702,0.00001163339,0.003608801,0.00001877712,0.00001228111,0.00328284],"study_design_scores_gemma":[0.006810086,0.004835,0.9627527,0.0004920881,0.0001471506,3.481736e-7,0.00002529725,0.00001202617,0.02476062,0.00002018835,0.000004883674,0.0001396236],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985172,0.0002217084,0.000004945162,0.00001055754,0.0001904476,0.0007974278,0.00002423398,0.00003967073,0.0001937889],"genre_scores_gemma":[0.9993106,0.000002427221,0.00005316365,0.0001417806,0.00005939798,0.00005015044,0.0002650357,0.00004356619,0.00007391522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02873844,"threshold_uncertainty_score":0.6800716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002466988403361013,"score_gpt":0.18984836130964,"score_spread":0.187381372906279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}