{"id":"W2107386898","doi":"10.1242/jcs.081596","title":"Evolutionary reconstruction of the retromer complex and its function in <i>Trypanosoma brucei</i>","year":2011,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Wellcome Trust","keywords":"Retromer; Endosome; Biology; Trypanosoma brucei; Cell biology; Vacuolar protein sorting; Transport protein; Sorting nexin; Golgi apparatus; Genetics; Intracellular; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002392068,0.0002835796,0.0002020125,0.001014476,0.0005680302,0.000898449,0.0002671668,0.0005952885,0.001154452],"category_scores_gemma":[0.0004423591,0.0001849171,0.0002198282,0.0007256178,0.0004880267,0.0004535107,0.0004537522,0.0005261525,0.0005144083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006188809,"about_ca_system_score_gemma":0.0003802543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001963551,"about_ca_topic_score_gemma":0.002270025,"domain_scores_codex":[0.9998895,0.000026515,0.000007587502,0.00003653251,0.00001948025,0.0000204488],"domain_scores_gemma":[0.999828,0.00002851346,0.00004972727,0.00002139837,0.00003354463,0.00003883119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009337006,0.0000565591,0.05587693,0.000408948,0.00007973069,0.00299288,0.001042947,0.001708441,0.8886549,0.005323004,0.0003473997,0.04257451],"study_design_scores_gemma":[0.00009002924,0.0006069326,0.7916313,0.0004562527,0.0003322852,0.01148289,0.002494699,0.01612127,0.105088,0.006664919,0.06490868,0.0001227558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836742,0.004592411,0.005710531,0.0003109903,0.00002943267,0.00002285844,0.0002826813,0.00007798812,0.005298966],"genre_scores_gemma":[0.9906977,0.002539025,0.004003978,0.0001471492,0.00002892267,0.00001355104,0.001029422,0.00004272542,0.001497463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001963551,"threshold_uncertainty_score":0.004490256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04841389978858061,"score_gpt":0.2723735463253976,"score_spread":0.223959646536817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}