{"id":"W2107402919","doi":"10.1186/1477-5751-12-3","title":"Human Endogenous Retrovirus K(HML-2) Gag and Env specific T-cell responses are not detected in HTLV-I-infected subjects using standard peptide screening methods","year":2013,"lang":"en","type":"article","venue":"Journal of Negative Results in BioMedicine","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Canada Research Chairs; University of Toronto","funders":"Fogarty International Center; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Ontario HIV Treatment Network","keywords":"Tropical spastic paraparesis; Immunology; Retrovirus; Biology; Virology; Endogenous retrovirus; Epitope; Human T-lymphotropic virus 1; Pathogenesis; Antigen; T cell; Virus; Immune system; Genetics; T-cell leukemia; Gene; Myelopathy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002230928,0.0003470949,0.0002255645,0.0002582762,0.0002727123,0.0003851885,0.000111777,0.0005380438,0.001938559],"category_scores_gemma":[0.000576676,0.000157729,0.0001120575,0.0001656999,0.0002440035,0.0001514122,0.0001458848,0.0003101468,0.0004354473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009146643,"about_ca_system_score_gemma":0.0001025257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007852423,"about_ca_topic_score_gemma":0.0008192858,"domain_scores_codex":[0.9997278,0.00004754164,0.00003015441,0.00009275786,0.00005496082,0.00004685629],"domain_scores_gemma":[0.9997962,0.00007587369,0.00003683713,0.00001845937,0.00002608537,0.00004653995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002032442,0.0005638585,0.5321699,0.0002173,0.0001078436,0.003083022,0.001687897,0.0001231422,0.4457361,0.00008197433,0.000327156,0.01386939],"study_design_scores_gemma":[0.0001314441,0.00402028,0.9416702,0.00004880221,0.0001233271,0.01038868,0.0008592674,0.0003701718,0.03997629,0.0001013171,0.002298035,0.00001225134],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998607,0.0002961114,0.0001542573,0.00001545256,0.000007764317,0.0000213724,0.0001039065,0.000006135162,0.0007881179],"genre_scores_gemma":[0.998974,0.00009356626,0.0001975011,0.00008032692,0.00001021827,0.00001629598,0.0002211683,0.000001734663,0.0004051852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001938559,"threshold_uncertainty_score":0.006485105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06315508870016946,"score_gpt":0.3211515628508809,"score_spread":0.2579964741507114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}