{"id":"W2107413452","doi":"10.2174/156720511796391845","title":"Tyrosol and Hydroxytyrosol Two Main Components of Olive Oil, Protect N2a Cells Against Amyloid-β-Induced Toxicity. Involvement of the NF-κB Signaling","year":2011,"lang":"en","type":"article","venue":"Current Alzheimer Research","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hydroxytyrosol; Tyrosol; Glutathione; Toxicity; Mediterranean diet; Oxidative stress; Programmed cell death; Chemistry; Pharmacology; Resveratrol; Biochemistry; Neuroprotection; Polyphenol; Antioxidant; Biology; Medicine; Internal medicine; Apoptosis; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009003503,0.0003266986,0.0002109639,0.0001666692,0.0001148191,0.0001802867,0.0001087957,0.0002528838,0.0008100854],"category_scores_gemma":[0.0001088117,0.00008923456,0.0003152586,0.0000878596,0.0001422332,0.0001810183,0.0001921709,0.0003175693,0.0001592939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001018828,"about_ca_system_score_gemma":0.0001367637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003880147,"about_ca_topic_score_gemma":0.0007703599,"domain_scores_codex":[0.999944,0.000009011104,0.000006115947,0.000014042,0.00001235017,0.00001449779],"domain_scores_gemma":[0.9998997,0.00001121529,0.00004321993,0.000007026197,0.00001619746,0.00002256989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002838326,0.00003777205,0.0005113425,0.0001229526,0.00001831388,0.0000610132,0.00002103986,0.00002750243,0.9961268,0.00005085297,0.00002627834,0.002712238],"study_design_scores_gemma":[0.00004188085,0.001693962,0.01510793,0.00003800675,0.00006387255,0.0005077009,0.00007496678,0.0003038301,0.975704,0.0001189305,0.006335202,0.000009729055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827256,0.01276093,0.00254238,0.0001279096,0.00005555413,0.00003545475,0.0003998759,0.00002855424,0.001323751],"genre_scores_gemma":[0.9877492,0.005893202,0.003101679,0.0001283236,0.00002502284,0.00004513902,0.0006158208,0.00001010985,0.002431505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008100854,"threshold_uncertainty_score":0.002709985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.218671628998226,"score_gpt":0.3660943704965954,"score_spread":0.1474227414983694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}