{"id":"W2107413452","doi":"10.2174/156720511796391845","title":"Tyrosol and Hydroxytyrosol Two Main Components of Olive Oil, Protect N2a Cells Against Amyloid-β-Induced Toxicity. Involvement of the NF-κB Signaling","year":2011,"lang":"en","type":"article","venue":"Current Alzheimer Research","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hydroxytyrosol; Tyrosol; Glutathione; Toxicity; Mediterranean diet; Oxidative stress; Programmed cell death; Chemistry; Pharmacology; Resveratrol; Biochemistry; Neuroprotection; Polyphenol; Antioxidant; Biology; Medicine; Internal medicine; Apoptosis; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008533919,0.0002917303,0.000362586,0.000120222,0.0001907145,0.0000250444,0.0007357774,0.0001509587,0.00003526808],"category_scores_gemma":[0.0001155366,0.0002380749,0.000180239,0.0002165346,0.0006431871,0.00001025925,0.0009111363,0.0004872411,0.00001288975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002853135,"about_ca_system_score_gemma":0.0001339338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001841097,"about_ca_topic_score_gemma":0.000094314,"domain_scores_codex":[0.9971859,0.0004741583,0.0005437818,0.0006214298,0.0005701475,0.0006045919],"domain_scores_gemma":[0.9983047,0.00005809776,0.0002660431,0.0007939909,0.000387087,0.0001901443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001801204,0.0004017738,0.001614736,0.0002277881,0.0002546322,4.312359e-7,0.0009072157,0.0000111506,0.9940896,0.00003168022,0.0002254019,0.002055491],"study_design_scores_gemma":[0.0008514537,0.0001919288,0.0003262479,0.0002454092,0.00005143235,0.000001108191,0.0001789749,0.00002551608,0.9963017,0.000202632,0.001376008,0.0002476304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993733,0.004535293,0.00007882871,0.00002464077,0.0002030081,0.0008324494,0.000128733,0.000006684632,0.0004573122],"genre_scores_gemma":[0.9981125,0.0008026686,0.000583938,0.00002632614,0.0001568682,0.0001043923,0.0001067909,0.00003909708,0.0000673964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004379473,"threshold_uncertainty_score":0.9708413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.218671628998226,"score_gpt":0.3660943704965954,"score_spread":0.1474227414983694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}