{"id":"W2107434078","doi":"10.1161/circresaha.108.178681","title":"Protein Kinase D Is a Key Regulator of Cardiomyocyte Lipoprotein Lipase Secretion After Diabetes","year":2008,"lang":"en","type":"article","venue":"Circulation Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Natural Sciences and Engineering Research Council of Canada","funders":"Canadian Diabetes Association","keywords":"Protein kinase C; Internal medicine; Endocrinology; Lipoprotein lipase; Protein kinase A; Phosphorylation; Kinase; Biology; Chemistry; Cell biology; Medicine; Adipose tissue","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005373649,0.0001159302,0.0001613224,0.0001749534,0.0001392307,0.00001406088,0.0001190076,0.0002414975,0.0003093187],"category_scores_gemma":[0.0002924874,0.000117369,0.0001222232,0.0002935065,0.000235676,0.000008457609,0.0000868834,0.0001661923,0.000063584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002507032,"about_ca_system_score_gemma":0.0001415622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007037764,"about_ca_topic_score_gemma":0.00001380779,"domain_scores_codex":[0.9982811,0.0003601278,0.000252401,0.0003969243,0.0004111539,0.0002983349],"domain_scores_gemma":[0.998796,0.00001567194,0.00006627553,0.0005225288,0.0004850253,0.0001145085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002411758,0.0000480551,0.01462927,0.0000551444,0.00002778227,0.00001055997,0.0001528921,0.00006536074,0.9824148,0.00007650719,0.001499572,0.0007788481],"study_design_scores_gemma":[0.0009267921,0.0003997475,0.07371952,0.00004745123,0.00000953816,0.00001752439,0.00003761015,0.000510347,0.8988025,0.0002696531,0.02502389,0.0002354791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996645,0.0004950204,0.0009656049,0.0002217975,0.0001065707,0.0006778823,0.00002477335,0.00001320784,0.0008501642],"genre_scores_gemma":[0.9968519,0.00002810937,0.0003811017,0.0000781016,0.0003925136,0.0002635959,0.0001085955,0.0000219238,0.00187415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08361237,"threshold_uncertainty_score":0.478617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03741271250078711,"score_gpt":0.2943350869643248,"score_spread":0.2569223744635377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}