{"id":"W2107439917","doi":"10.1016/j.cell.2012.11.053","title":"MITRAC Links Mitochondrial Protein Translocation to Respiratory-Chain Assembly and Translational Regulation","year":2012,"lang":"en","type":"article","venue":"Cell","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":265,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Howard Hughes Medical Institute","keywords":"Biology; Protein subunit; Mitochondrion; Respiratory chain; Cell biology; Biogenesis; Mitochondrial carrier; Cytosol; Translocase of the inner membrane; Biochemistry; Translocase; Cytochrome c oxidase; Mitochondrial respiratory chain; Inner mitochondrial membrane; Ribosome; Mitochondrial membrane transport protein; Gene; Chromosomal translocation; Bacterial outer membrane; RNA; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007090414,0.0005906767,0.0004050055,0.0006691317,0.00110675,0.001378962,0.0004902058,0.001114361,0.003189296],"category_scores_gemma":[0.0006049922,0.0003977925,0.0003791765,0.0004837406,0.0007393482,0.001540271,0.000790943,0.001457198,0.0009942609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001127085,"about_ca_system_score_gemma":0.0004561824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006252552,"about_ca_topic_score_gemma":0.0009988268,"domain_scores_codex":[0.9995298,0.00008339222,0.00003300861,0.0001163247,0.0001147556,0.000122698],"domain_scores_gemma":[0.999317,0.0001099509,0.0001638504,0.0001266596,0.0001061054,0.0001764098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005097776,0.0001033896,0.0007010698,0.00007920389,0.00001676061,0.0002796778,0.00005752581,0.0001395721,0.9918454,0.002946813,0.0006994951,0.002621338],"study_design_scores_gemma":[0.00003989786,0.0003482275,0.01737571,0.00002196659,0.00002939001,0.0007006263,0.00009255198,0.002080547,0.9690934,0.001623231,0.008570425,0.0000241121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9404463,0.02205002,0.02071255,0.004075879,0.0008033961,0.00008278957,0.00130385,0.0009364497,0.009588723],"genre_scores_gemma":[0.9881932,0.002647569,0.003007783,0.0003251669,0.0002177678,0.00004271197,0.0008073989,0.0001015449,0.004656822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003189296,"threshold_uncertainty_score":0.01066923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01523023890603566,"score_gpt":0.2456904028931749,"score_spread":0.2304601639871392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}