{"id":"W2107439917","doi":"10.1016/j.cell.2012.11.053","title":"MITRAC Links Mitochondrial Protein Translocation to Respiratory-Chain Assembly and Translational Regulation","year":2012,"lang":"en","type":"article","venue":"Cell","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":265,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Howard Hughes Medical Institute","keywords":"Biology; Protein subunit; Mitochondrion; Respiratory chain; Cell biology; Biogenesis; Mitochondrial carrier; Cytosol; Translocase of the inner membrane; Biochemistry; Translocase; Cytochrome c oxidase; Mitochondrial respiratory chain; Inner mitochondrial membrane; Ribosome; Mitochondrial membrane transport protein; Gene; Chromosomal translocation; Bacterial outer membrane; RNA; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001754729,0.000116144,0.0000924767,0.00005374345,0.000075706,0.00001514349,0.00005499876,0.0003218248,0.00006081264],"category_scores_gemma":[0.00003592396,0.0001201815,0.00004734593,0.00007259906,0.00002626549,0.000009137604,0.00001130958,0.0001084749,0.00004263457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004911104,"about_ca_system_score_gemma":0.00003701621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003487222,"about_ca_topic_score_gemma":0.0000152674,"domain_scores_codex":[0.9991669,0.000103546,0.0001865229,0.0002469038,0.0001019996,0.000194142],"domain_scores_gemma":[0.9995729,0.000009930736,0.00004534879,0.00017302,0.00005461348,0.000144225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001621228,0.00004420376,0.0003942678,0.0000110992,0.000005161993,1.942999e-7,0.0001879753,0.00003462133,0.9953591,0.0002048619,0.001664505,0.00193188],"study_design_scores_gemma":[0.0007136725,0.0001840766,0.003335411,0.000006861651,0.00001029226,0.000004521959,0.00002034748,0.00002819901,0.8178795,0.00005871527,0.1775953,0.0001631205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9156549,0.0008033682,0.07970376,0.0004443275,0.0007221117,0.0006080687,0.00001375375,0.00001965896,0.002030077],"genre_scores_gemma":[0.9885004,0.000007496119,0.007086209,0.0006203879,0.001667043,0.00006988129,0.0001264177,0.00002066738,0.00190149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1774796,"threshold_uncertainty_score":0.490086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01523023890603566,"score_gpt":0.2456904028931749,"score_spread":0.2304601639871392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}