{"id":"W2107449056","doi":"10.1017/s0317167100003929","title":"Pathology of Mitochondrial Encephalomyopathies","year":2005,"lang":"en","type":"review","venue":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Cedars-Sinai Medical Center","keywords":"Mitochondrial Encephalomyopathies; Cytochrome c oxidase; Mitochondrial myopathy; Biology; Respiratory chain; Mitochondrion; Muscle biopsy; Mitochondrial DNA; Mitochondrial respiratory chain; Mitochondrial disease; Pathology; Succinate dehydrogenase; Mitochondrial encephalomyopathy; Dihydrolipoamide dehydrogenase; MELAS syndrome; Molecular biology; Biochemistry; Biopsy; Enzyme; Dehydrogenase; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002296214,0.0008640022,0.0002687115,0.001675164,0.0002798238,0.0003766106,0.0001813066,0.0004601153,0.0045531],"category_scores_gemma":[0.000457578,0.0002294502,0.0001694486,0.0004031563,0.0003586621,0.0004726591,0.000405871,0.0002798415,0.001799967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001876369,"about_ca_system_score_gemma":0.0001301514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003921887,"about_ca_topic_score_gemma":0.0003457824,"domain_scores_codex":[0.9998897,0.00001821539,0.00001756506,0.00002620128,0.00003024297,0.00001803269],"domain_scores_gemma":[0.9997717,0.00003851853,0.00007071648,0.0000256285,0.00005526467,0.00003828575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009647121,0.000127165,0.1062686,0.001457037,0.0001832055,0.3067005,0.0008606379,0.0006424543,0.4194905,0.004446835,0.01096051,0.1478977],"study_design_scores_gemma":[0.0000315238,0.0002117329,0.2543053,0.0003678267,0.0001071695,0.6670777,0.0002935766,0.0007430304,0.03135123,0.00324922,0.04223054,0.00003110787],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.841775,0.05497189,0.01266912,0.001807316,0.0005015916,0.0001872249,0.002776893,0.00141877,0.08389214],"genre_scores_gemma":[0.9693314,0.0148101,0.004092714,0.0003338449,0.0001938009,0.00003742237,0.001130544,0.00005960326,0.0100105],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0045531,"threshold_uncertainty_score":0.01523167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0435082331034462,"score_gpt":0.30191611575634,"score_spread":0.2584078826528938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}