{"id":"W2107513762","doi":"10.4049/jimmunol.1000913","title":"Retinoic Acid-Induced CCR9 Expression Requires Transient TCR Stimulation and Cooperativity between NFATc2 and the Retinoic Acid Receptor/Retinoid X Receptor Complex","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Verband der Chemischen Industrie; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Uehara Memorial Foundation; Institute of Genetics; Naito Foundation","keywords":"Retinoid X receptor; Retinoid X receptor beta; Retinoid X receptor gamma; NFAT; Retinoic acid receptor; Retinoic acid; Biology; Transcription factor; Transactivation; Cell biology; Molecular biology; Retinoid X receptor alpha; Chemistry; Nuclear receptor; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002132363,0.0002933025,0.0005938495,0.0001572858,0.000772914,0.00004852286,0.0003726786,0.0004565439,0.001039199],"category_scores_gemma":[0.0006059117,0.0001654663,0.0001281707,0.0001433578,0.001108541,0.0003035305,0.0001421012,0.001899346,0.00007841724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004140775,"about_ca_system_score_gemma":0.00006258982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005206194,"about_ca_topic_score_gemma":0.00001514609,"domain_scores_codex":[0.9964001,0.002057871,0.0008599196,0.0002355932,0.0000946552,0.0003518884],"domain_scores_gemma":[0.9975414,0.0008789725,0.0008003037,0.0004098615,0.0003336351,0.00003583428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003921689,0.00005953034,0.000520506,0.000008566979,0.0002131227,6.037641e-7,0.002498225,0.000001814352,0.9817222,0.0001405713,0.003761797,0.007151407],"study_design_scores_gemma":[0.004785627,0.00102089,0.02821849,0.00007394791,0.0001624336,0.0005024778,0.0009255519,0.00001419115,0.9301037,0.00007453979,0.0339089,0.0002092477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880651,0.002781994,0.0003367685,0.004481462,0.003692034,0.0003655883,0.000006186438,0.00003449793,0.000236342],"genre_scores_gemma":[0.9979237,0.001001279,0.0001162993,0.0002320259,0.0001989943,0.000005816215,0.00004359342,0.00002483167,0.0004534471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05161847,"threshold_uncertainty_score":0.999874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02113365993363614,"score_gpt":0.2555937007233882,"score_spread":0.234460040789752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}