{"id":"W2107515797","doi":"10.1016/s0168-9525(00)02213-7","title":"Human morbid genetics revisited: relevance of epigenetics","year":2001,"lang":"en","type":"article","venue":"Trends in Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":251,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Biology; Epigenetics; Mendelian inheritance; Genetics; Gene; Identification (biology); Human genetics; DNA methylation; Disease; Epigenesis; Evolutionary biology; Computational biology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003174452,0.0002987142,0.0003356765,0.0002788885,0.00006833724,0.00001986315,0.0004138056,0.0003110646,0.00009246451],"category_scores_gemma":[0.00006019291,0.0003328203,0.0001431174,0.0005826135,0.0001585823,0.000003130796,0.0001786048,0.0001628119,0.000007725504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002684637,"about_ca_system_score_gemma":0.00004127952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001822356,"about_ca_topic_score_gemma":0.0001607955,"domain_scores_codex":[0.9978254,0.0001168809,0.0007454233,0.0005518364,0.0003126373,0.0004478166],"domain_scores_gemma":[0.9984952,0.00001969604,0.0002601602,0.0009304307,0.0001687182,0.0001257557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004140761,0.0002111916,0.1396346,0.00003414768,0.00004158948,0.00001191786,0.00009693356,0.006738832,0.7749647,0.0001410968,0.0004824436,0.0776011],"study_design_scores_gemma":[0.001435334,0.001026636,0.1988613,0.00005805984,0.00006387806,0.00001110517,0.00005027687,0.0008754682,0.7010846,0.001261253,0.09454698,0.0007251221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9715101,0.01950755,0.001322682,0.0000600563,0.0001531987,0.0001436837,0.00003019757,0.00001460213,0.007258004],"genre_scores_gemma":[0.9797503,0.01208123,0.005497226,0.00006150433,0.0002800172,0.00001335254,0.000189593,0.00006471207,0.0020621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09406454,"threshold_uncertainty_score":0.9999124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02817588163417053,"score_gpt":0.3256133841334296,"score_spread":0.297437502499259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}