{"id":"W2107623090","doi":"10.1189/jlb.0206099","title":"TLR4 gene dosage contributes to endotoxin-induced acute respiratory inflammation","year":2006,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Studium Loire Valley-Institute for Advanced Studies; Canadian Institutes of Health Research; Centre National de la Recherche Scientifique","keywords":"TLR4; Chemokine; Biology; Inflammation; Immunology; Lipopolysaccharide; Lung; Tumor necrosis factor alpha; Bronchoalveolar lavage; Cytokine; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009457528,0.0002056013,0.0005094304,0.0005388221,0.0001532287,0.00002294271,0.0003091946,0.0004282805,0.0001152092],"category_scores_gemma":[0.0002339789,0.0001663173,0.000189317,0.0002147961,0.00009236763,0.0001986477,0.00007008019,0.0003751479,0.0003754666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001863077,"about_ca_system_score_gemma":0.0002283762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000389201,"about_ca_topic_score_gemma":0.00001527024,"domain_scores_codex":[0.9978045,0.0005367515,0.001044888,0.0001792101,0.00004606533,0.0003885617],"domain_scores_gemma":[0.998437,0.0002359126,0.0007003824,0.0002339398,0.0003624913,0.00003030191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001247999,0.00003534863,0.0009952813,0.000004112693,0.0002829908,0.00003167924,0.00007620409,0.00001666157,0.987242,0.001812108,0.00261593,0.005639638],"study_design_scores_gemma":[0.002130435,0.0007119486,0.01223305,0.00002319386,0.00007400459,0.0002221114,0.00002840233,9.413833e-7,0.8269161,0.0005392975,0.1569813,0.0001392347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924,0.002712807,0.00172742,0.001033911,0.001406383,0.0002431472,0.000009503632,0.00003060831,0.000436239],"genre_scores_gemma":[0.9983932,0.00007279212,0.0001860558,0.0003689754,0.0003850299,0.00001111307,0.00004921549,0.0000160289,0.000517625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.160326,"threshold_uncertainty_score":0.6782224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01183117851780719,"score_gpt":0.2590383182717944,"score_spread":0.2472071397539872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}