{"id":"W2107656326","doi":"10.4049/jimmunol.179.2.837","title":"Transcriptional Analysis of Clonal Deletion In Vivo","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Fondation pour la Recherche Médicale","keywords":"Biology; Clonal deletion; Negative selection; T-cell receptor; Gene; Nerve growth factor IB; Transgene; Cell biology; Major histocompatibility complex; Genetics; Gene expression; CD8; Clonal selection; Transcription factor; T cell; Immune system; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001162011,0.00004645227,0.0001873132,0.0004196989,0.0000373092,0.000003421637,0.0002146807,0.00004352664,0.0005220557],"category_scores_gemma":[0.00009627231,0.00003074846,0.0001240874,0.0005569828,0.0001291042,0.00006439513,0.00001192005,0.0002160558,0.000002553042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002903212,"about_ca_system_score_gemma":0.00002101199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002278368,"about_ca_topic_score_gemma":0.0000248947,"domain_scores_codex":[0.9990776,0.0001742773,0.000412305,0.00004706602,0.0001649455,0.000123803],"domain_scores_gemma":[0.9993152,0.0002980464,0.000251784,0.00006827017,0.00005185476,0.0000148585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003852586,0.00005378326,0.0007447398,8.992413e-7,0.00006647693,0.00000673218,0.0004991521,0.0007549357,0.9939052,0.002144783,0.00001448745,0.001423521],"study_design_scores_gemma":[0.0008714662,0.0004303769,0.08397495,0.00002262163,0.0002971328,0.0002640373,0.000575288,0.0006843857,0.9083217,0.001083545,0.003380902,0.00009359025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963766,0.0002721113,0.002578916,0.0002336626,0.0001866165,0.00002139286,0.000001931529,0.000001918299,0.0003267989],"genre_scores_gemma":[0.9995372,0.0001758112,0.0001016162,0.0001177779,0.00002952517,6.756288e-8,1.307604e-7,0.00000368752,0.00003423819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08558353,"threshold_uncertainty_score":0.5716144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02255850646390519,"score_gpt":0.2654599432631743,"score_spread":0.2429014367992691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}