{"id":"W2107668920","doi":"10.4049/jimmunol.1004201","title":"Innate Immune Collectin Surfactant Protein D Simultaneously Binds Both Neutrophil Extracellular Traps and Carbohydrate Ligands and Promotes Bacterial Trapping","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Neutrophil extracellular traps; Collectin; Innate immune system; Biology; Microbiology; Ex vivo; In vivo; Extracellular; Pseudomonas aeruginosa; Surfactant protein A; Lipopolysaccharide; Immune system; Cell biology; Bacteria; Biochemistry; In vitro; Pulmonary surfactant; Immunology; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001643087,0.0003038618,0.0002788555,0.0001980165,0.0001150743,0.000240728,0.0001238169,0.0002510999,0.0007501831],"category_scores_gemma":[0.0001655937,0.0001146225,0.0002759155,0.00008439652,0.0001840445,0.0001989349,0.0003171198,0.0003726542,0.0002336394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002621011,"about_ca_system_score_gemma":0.0002482093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004263052,"about_ca_topic_score_gemma":0.000731989,"domain_scores_codex":[0.9997659,0.00004315961,0.00002416855,0.00003646079,0.00007942053,0.00005093915],"domain_scores_gemma":[0.9998285,0.00003076375,0.00003879139,0.00001601041,0.00002171547,0.00006432368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000606124,0.0000137251,0.0002369221,0.0000282606,0.000003392674,0.0000347491,0.000004954469,0.00001741088,0.9989582,0.00001682212,0.00001705313,0.0006079552],"study_design_scores_gemma":[0.00001637555,0.0004432463,0.007246024,0.000006733922,0.00001510151,0.0003908383,0.00003235987,0.0009866662,0.9896334,0.00003226459,0.001192706,0.0000042034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947808,0.001627928,0.002692264,0.00009348423,0.00001778848,0.00001670178,0.00009577639,0.00004178219,0.0006334657],"genre_scores_gemma":[0.9953845,0.000669559,0.002202987,0.00007920162,0.00001286725,0.0000235294,0.0002308091,0.00000871047,0.00138782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007501831,"threshold_uncertainty_score":0.002509594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01630379411857519,"score_gpt":0.1996517644549314,"score_spread":0.1833479703363562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}