{"id":"W2107668920","doi":"10.4049/jimmunol.1004201","title":"Innate Immune Collectin Surfactant Protein D Simultaneously Binds Both Neutrophil Extracellular Traps and Carbohydrate Ligands and Promotes Bacterial Trapping","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Neutrophil extracellular traps; Collectin; Innate immune system; Biology; Microbiology; Ex vivo; In vivo; Extracellular; Pseudomonas aeruginosa; Surfactant protein A; Lipopolysaccharide; Immune system; Cell biology; Bacteria; Biochemistry; In vitro; Pulmonary surfactant; Immunology; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001065509,0.0003713944,0.0007398658,0.0002808134,0.0004430567,0.00003204123,0.0004113948,0.0003417831,0.0001880313],"category_scores_gemma":[0.00009928513,0.0002455812,0.0001076906,0.000243035,0.0007214564,0.0001947075,0.0001565452,0.0009080519,0.00001236905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003583316,"about_ca_system_score_gemma":0.0001236252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001071606,"about_ca_topic_score_gemma":0.00001534561,"domain_scores_codex":[0.9976162,0.0007096726,0.0008482096,0.0002543624,0.0000604054,0.0005111752],"domain_scores_gemma":[0.9985508,0.0002200595,0.0007090291,0.0002945271,0.0001795646,0.0000460394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002601555,0.0001472091,0.00003211037,0.00001797043,0.0006597247,0.0001394579,0.003529556,0.000001030149,0.9903054,0.0005486035,0.000009050998,0.002008363],"study_design_scores_gemma":[0.002994464,0.003214082,0.001971515,0.000115145,0.0001950222,0.002812971,0.0008008645,0.000006307322,0.9858165,0.0009310132,0.0008547822,0.0002873084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834973,0.01484423,0.00009181522,0.0004164657,0.0005769017,0.0004545535,0.00001242528,0.00002837145,0.00007800107],"genre_scores_gemma":[0.9979815,0.001273733,0.000151589,0.00003773182,0.00005477355,0.000008560571,0.000005385911,0.00004034262,0.0004463485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0144843,"threshold_uncertainty_score":0.9999996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01630379411857519,"score_gpt":0.1996517644549314,"score_spread":0.1833479703363562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}