{"id":"W2107700722","doi":"10.1186/1742-4690-8-72","title":"HIV infection of thymocytes inhibits IL-7 activity without altering CD127 expression","year":2011,"lang":"en","type":"article","venue":"Retrovirology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Ontario HIV Treatment Network; Canadian Foundation for AIDS Research","keywords":"Interleukin-7 receptor; Downregulation and upregulation; CD8; Immunology; Biology; In vitro; Receptor; Immune system; Cell biology; T cell; IL-2 receptor; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002244359,0.0002605282,0.0005275629,0.0002252265,0.0001561534,0.000003687463,0.000219274,0.0006756788,0.0009247967],"category_scores_gemma":[0.00007698309,0.0002269751,0.0001344236,0.000125291,0.0005190981,0.0001595085,0.0002466486,0.0005342843,0.0004903575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000372859,"about_ca_system_score_gemma":0.00004209454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004614344,"about_ca_topic_score_gemma":0.00003251498,"domain_scores_codex":[0.9982445,0.0004064815,0.0003646659,0.0004463292,0.00003488145,0.0005032037],"domain_scores_gemma":[0.9990374,0.0001032021,0.0003127106,0.0004563562,0.00006312712,0.00002714056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006527801,0.0002678885,0.07673737,0.00002842974,0.00009452931,0.000004148993,0.0005082483,0.000002024512,0.9191048,0.0001851375,0.0001967593,0.002217946],"study_design_scores_gemma":[0.00127934,0.0008274986,0.02814976,0.00002632054,0.00004607801,0.0001232623,0.00003067058,0.000005277936,0.9662864,0.0001857262,0.00283574,0.0002039124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937248,0.000532499,0.0007253799,0.00003601846,0.0009901574,0.0001853044,0.0000171761,0.0001388886,0.003649818],"genre_scores_gemma":[0.9982818,0.0001964471,0.0001603735,0.00005720458,0.00004289324,0.00002362028,0.0000276165,0.00002727359,0.001182717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0485876,"threshold_uncertainty_score":0.9999885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02067202748092135,"score_gpt":0.2252684745168455,"score_spread":0.2045964470359241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}