{"id":"W2107724124","doi":"10.1039/c5cc01949d","title":"Diastereoselective construction of anti-4,5-disubstituted-1,3-dioxolanes via a bismuth-mediated two-component hemiacetal oxa-conjugate addition of γ-hydroxy-α,β-unsaturated ketones with paraformaldehyde","year":2015,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Engineering and Physical Sciences Research Council; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Paraformaldehyde; Hemiacetal; Conjugate; Chemistry; Component (thermodynamics); Bismuth; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001230815,0.0003530046,0.0001373721,0.0001973631,0.0001039963,0.0002018244,0.0002965845,0.0001642934,0.001120361],"category_scores_gemma":[0.00008443927,0.0001374329,0.0001178434,0.0001228025,0.0001472967,0.000236107,0.0002083659,0.0002851539,0.000324758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002541651,"about_ca_system_score_gemma":0.000256161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003517052,"about_ca_topic_score_gemma":0.0008461652,"domain_scores_codex":[0.9999349,0.000006822809,0.000005070407,0.00001285311,0.0000161049,0.00002416622],"domain_scores_gemma":[0.9999526,0.00000436605,0.00001617331,0.000005672874,0.000008977045,0.00001228974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005836899,0.00001930977,0.0001228467,0.00004389956,0.000004773846,0.0001051412,0.00003447862,0.0001142155,0.9954321,0.0009738284,0.00006062219,0.003030313],"study_design_scores_gemma":[0.000008186918,0.0001674829,0.0003537032,0.0000024632,0.000006345429,0.0001228377,0.00001234863,0.0001648184,0.9964241,0.00005232744,0.002680678,0.000004592134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98291,0.000658876,0.008946748,0.00007190257,0.00004869665,0.00005422333,0.0002639892,0.0001175555,0.006927883],"genre_scores_gemma":[0.9902827,0.0006353917,0.005504104,0.00002756432,0.000006243998,0.00002421354,0.0002134384,0.00002268326,0.003283742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001120361,"threshold_uncertainty_score":0.003748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02979993308147244,"score_gpt":0.2756934635192194,"score_spread":0.245893530437747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}