{"id":"W2107757630","doi":"10.1128/jb.184.10.2699-2708.2002","title":"A Quorum-Sensing Signaling System Essential for Genetic Competence in <i>Streptococcus mutans</i> Is Involved in Biofilm Formation","year":2002,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":477,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; Ontario Innovation Trust","keywords":"Biofilm; Quorum sensing; Biology; Mutant; Streptococcus gordonii; Complementation; Microbiology; Streptococcus mutans; Wild type; Gene; Protein-fragment complementation assay; Genetics; Cell biology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003214256,0.0001824289,0.0004126256,0.0001973737,0.00005130026,0.00003697033,0.0001485255,0.000263117,0.00001267419],"category_scores_gemma":[0.00006958099,0.0001713213,0.0001374035,0.0001507742,0.00006771504,0.00002173064,0.00004498941,0.0001633851,0.000002666522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000674413,"about_ca_system_score_gemma":0.00004985022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002544384,"about_ca_topic_score_gemma":0.00008369629,"domain_scores_codex":[0.9982866,0.0001458785,0.0009041888,0.0002271287,0.00008320223,0.000352983],"domain_scores_gemma":[0.9990211,0.0000376627,0.0005268957,0.000162622,0.0001820438,0.00006970228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002106347,0.00003634325,0.002598552,0.00006648179,0.0000220793,0.00003747685,0.0001797083,0.0001069088,0.9946551,0.000008246542,0.0001147292,0.001963758],"study_design_scores_gemma":[0.00342267,0.001129456,0.00656046,0.0004739117,0.00004182127,0.0007953742,0.0007567185,0.007274996,0.9756205,0.00001978576,0.003484257,0.0004200478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973825,0.0003990185,0.001152645,0.0002374701,0.0005290647,0.0002470064,0.00001554752,0.00000479972,0.00003189847],"genre_scores_gemma":[0.993561,0.0001114282,0.005631863,0.000225231,0.0004217052,0.000002979026,0.00001909516,0.00001920828,0.000007491823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01903458,"threshold_uncertainty_score":0.698628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01365751161751266,"score_gpt":0.225742783013624,"score_spread":0.2120852713961114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}