{"id":"W2107790115","doi":"10.1261/rna.1557809","title":"The XIAP IRES activates 3′ cistron expression by inducing production of monocistronic mRNA in the βgal/CAT bicistronic reporter system","year":2009,"lang":"en","type":"letter","venue":"RNA","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Internal ribosome entry site; Cistron; Biology; XIAP; Messenger RNA; Translation (biology); Cell biology; Plasmid; Molecular biology; RNA splicing; Genetics; Gene; RNA; Apoptosis; Programmed cell death","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002254295,0.0002544095,0.0001950661,0.0001288526,0.000218573,0.0004164012,0.0001665154,0.0009613374,0.002140906],"category_scores_gemma":[0.0004584306,0.00009586078,0.0001320177,0.0001109558,0.0003430474,0.0002136415,0.0001448897,0.001453499,0.001400446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000484425,"about_ca_system_score_gemma":0.0001222905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001558893,"about_ca_topic_score_gemma":0.0001802114,"domain_scores_codex":[0.999806,0.00008136926,0.00001309925,0.00002705665,0.00004016834,0.0000323717],"domain_scores_gemma":[0.999809,0.00009606231,0.00002159798,0.00003541327,0.00002167631,0.00001628323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001795324,0.0003878219,0.005597793,0.0004263296,0.00003125608,0.04922646,0.0004289057,0.0005950593,0.788939,0.01476884,0.04866674,0.08913652],"study_design_scores_gemma":[0.0006481289,0.001715608,0.01134355,0.0001166539,0.00005786827,0.09934034,0.0005028731,0.009935085,0.5601613,0.006489332,0.3096435,0.00004574152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7818679,0.009542717,0.02016321,0.07639132,0.005758414,0.0003067521,0.0004233922,0.001085288,0.1044609],"genre_scores_gemma":[0.940155,0.003976544,0.006190892,0.01201751,0.002407495,0.0001402408,0.0001996204,0.00004733553,0.03486542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002140906,"threshold_uncertainty_score":0.007162035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02160454855579785,"score_gpt":0.2934682009385404,"score_spread":0.2718636523827426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}