{"id":"W2107822667","doi":"10.1161/01.hyp.36.4.506","title":"Enhanced Expression of Angiotensin II Type 2 Receptor, Inositol 1,4,5-Trisphosphate Receptor, and Protein Kinase Cε During Cardioprotection Induced by Angiotensin II Type 2 Receptor Blockade","year":2000,"lang":"en","type":"article","venue":"Hypertension","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Protein kinase C; Angiotensin II; Downregulation and upregulation; Endocrinology; Internal medicine; Receptor; Cardioprotection; Messenger RNA; Chemistry; Inositol; Protein kinase A; Kinase; Biology; Medicine; Ischemia; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004216415,0.0007634601,0.001633573,0.0003328989,0.0008760909,0.00003576348,0.0001656509,0.0007712023,0.0002693591],"category_scores_gemma":[0.0003415002,0.0006557898,0.0002997962,0.001166733,0.00020976,0.0002776561,0.0002968767,0.0006313971,0.0001410636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002364696,"about_ca_system_score_gemma":0.0001192523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006020135,"about_ca_topic_score_gemma":0.00000757256,"domain_scores_codex":[0.9956684,0.0002976216,0.001064743,0.001240427,0.0009234138,0.0008054517],"domain_scores_gemma":[0.9968064,0.00005922854,0.0004554151,0.001009777,0.001280449,0.0003886858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003447346,0.0002830559,0.0003251119,0.0000929641,0.0001970742,0.00002704972,0.0009950973,0.000005994955,0.9613907,0.000001053564,0.02570089,0.007533632],"study_design_scores_gemma":[0.003307531,0.001997164,0.004242714,0.002434559,0.0002367905,0.0001875449,0.0001579101,0.00005601559,0.9653745,0.000004343245,0.02133413,0.0006668347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881302,0.006481945,0.000009929629,0.001422334,0.0009572146,0.002418083,0.00002524266,0.0003293679,0.0002257338],"genre_scores_gemma":[0.9900129,0.00116319,0.003568497,0.0001494939,0.0005359688,0.00005181248,0.0001167141,0.0001672322,0.004234186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006866797,"threshold_uncertainty_score":0.9995893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01478235657687063,"score_gpt":0.2305401067744547,"score_spread":0.2157577501975841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}