{"id":"W2107901901","doi":"10.1128/jb.187.18.6309-6316.2005","title":"Adenylate Cyclase Mutations Rescue the <i>degP</i> Temperature-Sensitive Phenotype and Induce the Sigma E and Cpx Extracytoplasmic Stress Regulons in <i>Escherichia coli</i>","year":2005,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Department of Education of Guangdong Province","keywords":"Regulon; Sigma factor; Biology; Mutant; SOS response; Bacterial outer membrane; Escherichia coli; Periplasmic space; lac operon; Molecular biology; Mutation; Gene; Genetics; RNA polymerase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006964114,0.0005374603,0.0002420182,0.0001995319,0.0001308092,0.0002765386,0.0002423638,0.0002314248,0.001133181],"category_scores_gemma":[0.0001455405,0.0001973033,0.0002693862,0.0001480115,0.0002640812,0.0001047647,0.0002642227,0.0008436674,0.0004780714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004850823,"about_ca_system_score_gemma":0.0004712772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002573976,"about_ca_topic_score_gemma":0.002884523,"domain_scores_codex":[0.9998696,0.000016053,0.00002059179,0.0000258413,0.00003652684,0.00003139156],"domain_scores_gemma":[0.9998296,0.00002448132,0.00005382391,0.00002287254,0.00001615717,0.00005286967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002026631,0.000009454135,0.00009075403,0.000008666357,0.000001415843,0.00003489971,0.000004482748,0.00003733154,0.9994748,0.00003494834,0.00001562538,0.0002673784],"study_design_scores_gemma":[0.000009409177,0.0000635247,0.003943919,0.000004427295,0.000006838608,0.0002649974,0.00002420082,0.0006252905,0.993969,0.00002498931,0.001057184,0.0000062545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947245,0.000263742,0.002980592,0.0001134642,0.00003144759,0.0000369907,0.0006959653,0.0001213906,0.001031865],"genre_scores_gemma":[0.9908597,0.0002772343,0.004614015,0.0000838011,0.000009672745,0.00003376252,0.001366951,0.00008147145,0.002673449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002573976,"threshold_uncertainty_score":0.005117953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006037584054953435,"score_gpt":0.2208586509259411,"score_spread":0.2148210668709876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}