{"id":"W2107985230","doi":"10.1200/jco.2005.09.050","title":"Efficacy and Tolerability of Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer After Moderately Emetogenic Chemotherapy","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Nausea and vomiting management","field":"Medicine","cited_by":465,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Aprepitant; Medicine; Tolerability; Nausea; Vomiting; Chemotherapy; Palonosetron; Breast cancer; Oncology; Internal medicine; Chemotherapy-induced nausea and vomiting; Cancer; Antiemetic; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008047133,0.0001597289,0.0007630701,0.00009830111,0.0001249145,0.0002284348,0.0001873153,0.000198209,0.0006959139],"category_scores_gemma":[0.001801154,0.00009726424,0.000354781,0.0001289986,0.0001726874,0.0002091164,0.0001331095,0.0003647016,0.0001088527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001830602,"about_ca_system_score_gemma":0.0003107947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001850813,"about_ca_topic_score_gemma":0.0005302845,"domain_scores_codex":[0.9995333,0.0002988586,0.00005162579,0.00002666851,0.00006092765,0.00002867241],"domain_scores_gemma":[0.999293,0.0002341878,0.0002716722,0.00002592674,0.00004098939,0.0001341594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.434593,0.01067041,0.15264,0.001216954,0.001807081,0.0004728375,0.0003478066,0.002205001,0.0440894,0.0001058496,0.001309422,0.3505422],"study_design_scores_gemma":[0.05941953,0.543916,0.3779537,0.0001429236,0.001135544,0.001962492,0.0001737281,0.001962553,0.008466212,0.0001031913,0.004728897,0.00003528335],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971564,0.002124353,0.0001100877,0.00008185769,0.00001708342,0.0001035406,0.00004647265,0.000005701613,0.0003544545],"genre_scores_gemma":[0.9988341,0.0005321828,0.0002525165,0.000111621,0.00003351404,0.00005577696,0.00007666055,0.000001110575,0.0001025523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008047133,"threshold_uncertainty_score":0.004255772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06944337990183506,"score_gpt":0.4266040199115751,"score_spread":0.3571606400097401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}