{"id":"W2108012124","doi":"10.1016/j.molonc.2013.03.005","title":"Blocking the attachment of cancer cells in vivo with DNA aptamers displaying anti‐adhesive properties against the carcinoembryonic antigen","year":2013,"lang":"en","type":"article","venue":"Molecular Oncology","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research","keywords":"Aptamer; Carcinoembryonic antigen; Cancer cell; Cell adhesion; Cancer research; In vivo; Cancer; Cell; DNA; Adhesion; Antigen; Chemistry; Cell biology; Biology; Molecular biology; Immunology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001904132,0.0002024199,0.0002757233,0.00005367636,0.0001153942,0.00001759179,0.0003024882,0.0001396909,0.000003460673],"category_scores_gemma":[0.00001541032,0.0001033395,0.0001058893,0.0001944782,0.0004424997,0.000004735784,0.0001152806,0.0001632011,0.000001055609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005427334,"about_ca_system_score_gemma":0.0001302883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005255971,"about_ca_topic_score_gemma":0.0005246584,"domain_scores_codex":[0.998735,0.0001570076,0.0002757292,0.0003424316,0.0001598937,0.0003300019],"domain_scores_gemma":[0.9991721,0.00002000782,0.0002076694,0.0004312579,0.0001325479,0.00003642049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003396161,0.00005245605,0.007513063,0.00001310442,0.0001288033,0.00001358234,0.0001481636,0.0005262682,0.9889727,0.0000105755,0.0001471113,0.002440208],"study_design_scores_gemma":[0.0002556072,0.0002478284,0.002595006,0.00004699169,0.00005207491,0.000007480095,0.0005632148,0.0002572855,0.9931263,0.00001136923,0.002669506,0.000167376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967529,0.001107806,0.0003100967,0.0009487167,0.00004447166,0.0005267759,0.000005979846,0.00001177917,0.0002914468],"genre_scores_gemma":[0.9975445,0.0008876998,0.000384452,0.0009301079,0.00004019928,0.0001023444,0.000006520683,0.00002307218,0.00008113493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004918057,"threshold_uncertainty_score":0.4214062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009159672317581498,"score_gpt":0.2646279128502511,"score_spread":0.2554682405326695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}