{"id":"W2108017448","doi":"10.1073/pnas.1304127111","title":"Accessory factors promote AlfA-dependent plasmid segregation by regulating filament nucleation, disassembly, and bundling","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences","keywords":"Plasmid; Operon; Bacillus subtilis; Biology; DNA; Protein filament; Gene; Bacteria; Genetics; Computational biology; Cell biology; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002183551,0.0005294616,0.0001915529,0.0003764464,0.0002406273,0.0007842417,0.0001753072,0.0002397573,0.001646708],"category_scores_gemma":[0.0004074521,0.0002922526,0.0002874353,0.0001086127,0.0002902411,0.000330663,0.0006885175,0.0005206066,0.001081694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007609385,"about_ca_system_score_gemma":0.0003005837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000904028,"about_ca_topic_score_gemma":0.00165579,"domain_scores_codex":[0.9997851,0.00002604486,0.0000144034,0.00004402539,0.0000804387,0.00004990662],"domain_scores_gemma":[0.9995698,0.00006093406,0.0001090521,0.00003405181,0.00006462864,0.0001615113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001202935,0.00001978568,0.0006182988,0.0000203765,0.000003352203,0.00004480042,0.00002038737,0.00004562451,0.9969712,0.0002121673,0.00007912485,0.001844516],"study_design_scores_gemma":[0.00003022908,0.0001489178,0.01722842,0.00001506672,0.00001441781,0.000213584,0.00006151906,0.003045804,0.9721749,0.0002440413,0.006812771,0.00001034323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846125,0.00296951,0.006656,0.0001884834,0.00004494036,0.00003869301,0.0002091384,0.0004798523,0.004800929],"genre_scores_gemma":[0.9909943,0.000651912,0.003632263,0.00006036597,0.00002568134,0.00002046391,0.0002804168,0.0001290225,0.004205626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001646708,"threshold_uncertainty_score":0.005521059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01818102864678092,"score_gpt":0.2649508572678987,"score_spread":0.2467698286211178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}