{"id":"W2108022314","doi":"10.1086/513276","title":"Topical Resiquimod 0.01% Gel Decreases Herpes Simplex Virus Type 2 Genital Shedding: A Randomized, Controlled Trial","year":2007,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; U.S. Public Health Service","keywords":"Herpes simplex virus; Viral shedding; Immune system; Internal medicine; Immunology; Lesion; Virus; Medicine; Gastroenterology; Biology; Virology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001864728,0.0014729,0.0038488,0.0006178619,0.0005275946,0.001037648,0.001152599,0.002201191,0.007341266],"category_scores_gemma":[0.00270576,0.0006457271,0.001648253,0.0005949461,0.00112672,0.0009956075,0.0002915557,0.001742247,0.0007824573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005887846,"about_ca_system_score_gemma":0.00114632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001171143,"about_ca_topic_score_gemma":0.002264947,"domain_scores_codex":[0.9990038,0.0004991702,0.00009485259,0.0001895447,0.0001075725,0.0001051558],"domain_scores_gemma":[0.99898,0.0003769061,0.000283415,0.00005971863,0.0001157919,0.0001842186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9662635,0.005796422,0.0002887482,0.003645381,0.00148083,0.00003762011,0.00003923001,0.000142768,0.002448891,0.00006824677,0.0009172898,0.01887099],"study_design_scores_gemma":[0.9681294,0.02974435,0.0007531595,0.00009133881,0.0004898668,0.00001697525,0.00001358879,0.0001416739,0.0001837635,0.0000381495,0.0003898102,0.000007955518],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9318871,0.04186947,0.001579744,0.001618829,0.002467562,0.01366506,0.002419736,0.0004309589,0.004061683],"genre_scores_gemma":[0.9572147,0.01753558,0.003276434,0.002004891,0.001559666,0.01267184,0.001161476,0.00004324662,0.004532123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007341266,"threshold_uncertainty_score":0.02455896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01290353853719284,"score_gpt":0.3080453967952822,"score_spread":0.2951418582580894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}