{"id":"W2108138142","doi":"10.1128/aem.68.11.5671-5684.2002","title":"Cloning and Characterization of a Gene Cluster Involved in Cyclopentanol Metabolism in <i>Comamonas</i> sp. Strain NCIMB 9872 and Biotransformations Effected by <i>Escherichia coli</i> -Expressed Cyclopentanone 1,2-Monooxygenase","year":2002,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; University of New Brunswick; Biotechnology Research Institute","funders":"","keywords":"Monooxygenase; Biology; Gene cluster; Escherichia coli; Cyclopentanone; Dehydrogenase; Gene; Biochemistry; Alcohol dehydrogenase; Pseudomonas putida; Open reading frame; Microbiology; Enzyme; Cytochrome P450; Peptide sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001135104,0.0001985218,0.0002623467,0.00006768243,0.00004128198,0.00001126486,0.00005895549,0.0001819721,0.000009611924],"category_scores_gemma":[0.00000288424,0.0001996597,0.00001988163,0.00007834325,0.0001518187,0.00001322629,0.00006040525,0.000107847,0.000001047042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001195963,"about_ca_system_score_gemma":0.000003180581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002698845,"about_ca_topic_score_gemma":0.00001836398,"domain_scores_codex":[0.9990394,0.00005592402,0.0003025846,0.0003643945,0.00002635023,0.0002114159],"domain_scores_gemma":[0.9997439,0.000005620312,0.00007730674,0.000120214,0.000002669469,0.00005026911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006396863,0.0001182534,0.001113879,0.00003327459,0.0000217962,5.860533e-7,0.0001969753,0.00001090747,0.9975045,0.000006764739,0.00002599975,0.0009031093],"study_design_scores_gemma":[0.001880237,0.00006375669,0.02014503,0.00001367797,0.00001887912,0.00001809845,0.00008255651,0.00006154329,0.973437,0.000003482802,0.004055781,0.0002199678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973424,0.00154643,0.0001567775,0.00007181615,0.0000416574,0.0004549568,0.0003533914,0.000006805937,0.0000257296],"genre_scores_gemma":[0.9938233,0.004207189,0.0003506912,0.0002092164,0.00002855423,0.00003896451,0.001301849,0.00001804639,0.00002216264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0240675,"threshold_uncertainty_score":0.8141887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002688470833750174,"score_gpt":0.154696967058851,"score_spread":0.1520084962251008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}