{"id":"W2108153267","doi":"10.1136/ard.2007.077800","title":"Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis","year":2007,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":188,"is_retracted":false,"has_abstract":false,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"","keywords":"MMP3; Cartilage; Inflammation; S100A9; Arthritis; Medicine; ADAMTS; S100A8; Matrix metalloproteinase; Immunology; Thrombospondin; Aggrecan; Cartilage oligomeric matrix protein; Osteoarthritis; Pathology; Metalloproteinase; Internal medicine; Biology; Anatomy; Gene expression; Articular cartilage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001598776,0.0002354923,0.0001822171,0.0004064983,0.0002112586,0.0003116532,0.0001552939,0.0004106463,0.001262199],"category_scores_gemma":[0.0001422105,0.0001956178,0.0001817381,0.0001475402,0.0003109921,0.0003290943,0.0002282428,0.00058578,0.0003867261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003654102,"about_ca_system_score_gemma":0.0001384893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003297224,"about_ca_topic_score_gemma":0.0005914202,"domain_scores_codex":[0.9998645,0.00002903035,0.000009696003,0.00001546892,0.00003351867,0.0000478261],"domain_scores_gemma":[0.9999003,0.00001256801,0.00003052838,0.00000614381,0.00001442172,0.00003598048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006720822,0.00002486436,0.0006953564,0.00001963408,0.000004011122,0.0001642589,0.00001665563,0.00005438428,0.9963349,0.000292045,0.00006327788,0.001658388],"study_design_scores_gemma":[0.0001494392,0.0006836065,0.08038679,0.00001657212,0.00005640873,0.001681151,0.0002450914,0.002778769,0.9075281,0.00114896,0.005311328,0.00001389681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938579,0.00321591,0.001351139,0.000193286,0.00003969878,0.00001226234,0.00008292691,0.00004210145,0.001204803],"genre_scores_gemma":[0.9962352,0.0007080535,0.0006274711,0.00004003336,0.00001628205,0.00001022758,0.00008350793,0.000008637788,0.002270607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001262199,"threshold_uncertainty_score":0.004222453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01591265102357815,"score_gpt":0.2463949256597664,"score_spread":0.2304822746361883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}