{"id":"W2108182367","doi":"10.1093/toxsci/kfr255","title":"Standardized Extracts of Bacopa monniera Protect Against MPP+- and Paraquat-Induced Toxicity by Modulating Mitochondrial Activities, Proteasomal Functions, and Redox Pathways","year":2011,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Medicinal Plants and Neuroprotection","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Paraquat; Toxicity; Chemistry; Mitochondrion; Pharmacology; Redox; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001046191,0.0007006567,0.0005941624,0.0008017211,0.0002382208,0.00036286,0.0002271352,0.0004090546,0.001188845],"category_scores_gemma":[0.0001643175,0.0001301245,0.0003766038,0.0003997325,0.0002057377,0.0003799914,0.0003025903,0.0007478775,0.0002226332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001781072,"about_ca_system_score_gemma":0.0002259769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001190793,"about_ca_topic_score_gemma":0.001501635,"domain_scores_codex":[0.9999176,0.00001477683,0.000008955541,0.00001565641,0.00002333791,0.00001967212],"domain_scores_gemma":[0.9998993,0.00001119393,0.00002893929,0.000009583065,0.00002175913,0.00002913237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002707053,0.00008542347,0.0001596065,0.0001411237,0.000028168,0.00006991696,0.00001799175,0.0000579075,0.9967464,0.00004669205,0.0000322953,0.002343786],"study_design_scores_gemma":[0.000106645,0.004039357,0.02471663,0.00009577022,0.0003483776,0.0007738532,0.0001276083,0.000615554,0.9600709,0.0002791492,0.008797604,0.00002855344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978869,0.01630609,0.001854728,0.0002217258,0.00007216405,0.00009388317,0.0005376713,0.0001200248,0.001924756],"genre_scores_gemma":[0.9913134,0.003968423,0.001848877,0.0002623923,0.00004465685,0.00004299123,0.0009205681,0.00001595846,0.00158283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001190793,"threshold_uncertainty_score":0.00397706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07627495763538461,"score_gpt":0.2760135310469369,"score_spread":0.1997385734115523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}