{"id":"W2108216694","doi":"10.1016/j.jalz.2011.05.2351","title":"Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup","year":2011,"lang":"en","type":"review","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":830,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto","funders":"National Institute on Aging","keywords":"Medicine; Workgroup; Hyperintensity; Clinical trial; Subclinical infection; Pathology; Disease; Amyloidosis; Etiology; Hemosiderin; Magnetic resonance imaging; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03887576,0.001840558,0.008339701,0.003491601,0.0007891373,0.004367131,0.004667005,0.006485445,0.004656281],"category_scores_gemma":[0.04437475,0.001093169,0.005935372,0.003615666,0.001212799,0.003226405,0.001664032,0.008221531,0.001795254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004412513,"about_ca_system_score_gemma":0.01300842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006478852,"about_ca_topic_score_gemma":0.02264326,"domain_scores_codex":[0.9909575,0.003495959,0.002789231,0.0005571183,0.001892184,0.0003079794],"domain_scores_gemma":[0.952193,0.03044365,0.006665384,0.0006847869,0.008715837,0.001297261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002935315,0.000164554,0.0007092619,0.1192828,0.003043545,0.0001686781,0.0001990188,0.0004703028,0.0007573483,0.00286799,0.1365714,0.7328299],"study_design_scores_gemma":[0.006033836,0.0007244022,0.00620215,0.3148249,0.02023198,0.0004591071,0.0003392079,0.001009847,0.0009041062,0.009600597,0.6395161,0.0001538192],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003307289,0.9760228,0.001182095,0.01656256,0.002634927,0.0008154216,0.0006872045,0.00005709053,0.001707153],"genre_scores_gemma":[0.004739235,0.9657331,0.01092211,0.01319146,0.001689874,0.001463356,0.0008532587,0.00003610415,0.001371527],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03887576,"threshold_uncertainty_score":0.2055971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3162975470163162,"score_gpt":0.4552623431437465,"score_spread":0.1389647961274303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}