{"id":"W2108222064","doi":"10.1242/jcs.117663","title":"Bem3, a Cdc42 GTPase-Activating Protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes","year":2013,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of General Medical Sciences; National Science Foundation","keywords":"Rab; Biology; Cell biology; CDC42; Cell polarity; Endocytic cycle; GTPase; Intracellular; Cytokinesis; GTPase-activating protein; Vesicular transport protein; Secretory pathway; Small GTPase; Endocytosis; Vesicle; Cell division; Cell; Signal transduction; G protein; Biochemistry; Endoplasmic reticulum; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009443202,0.0001444844,0.0001646812,0.00009136227,0.0002424484,0.0001288867,0.0003885957,0.00005692105,0.00003509104],"category_scores_gemma":[0.00006853335,0.0001009292,0.0000598933,0.0002440455,0.0001628996,0.00004255374,0.00005828401,0.00015464,0.000005898478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002927769,"about_ca_system_score_gemma":0.0001782885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001969204,"about_ca_topic_score_gemma":0.00002018362,"domain_scores_codex":[0.9986346,0.00006391732,0.000339613,0.0002678847,0.0004023648,0.0002916291],"domain_scores_gemma":[0.9988885,0.00001535695,0.0001856921,0.000239913,0.0002710131,0.0003995102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006441336,0.00006604644,0.0002467194,0.00001548736,0.000005770306,0.000007579551,0.0007924135,0.0004447856,0.9961656,0.000008007769,0.00005434256,0.002128829],"study_design_scores_gemma":[0.0003948302,0.0009373143,0.002614977,0.00003747971,0.00001169279,0.00004630386,0.0007741475,0.0004828554,0.972969,0.00001995716,0.02154001,0.0001714436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917355,0.0003042332,0.006432739,0.0006721423,0.0001269619,0.0005756171,0.000002178914,0.000004581505,0.0001460405],"genre_scores_gemma":[0.9966394,0.00003062409,0.002662083,0.0002745194,0.0001952815,0.00001847484,0.00001156452,0.00001128417,0.0001567567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02319661,"threshold_uncertainty_score":0.4115772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01196805425506261,"score_gpt":0.2361384438021422,"score_spread":0.2241703895470796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}