{"id":"W2108222064","doi":"10.1242/jcs.117663","title":"Bem3, a Cdc42 GTPase-Activating Protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes","year":2013,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of General Medical Sciences; National Science Foundation","keywords":"Rab; Biology; Cell biology; CDC42; Cell polarity; Endocytic cycle; GTPase; Intracellular; Cytokinesis; GTPase-activating protein; Vesicular transport protein; Secretory pathway; Small GTPase; Endocytosis; Vesicle; Cell division; Cell; Signal transduction; G protein; Biochemistry; Endoplasmic reticulum; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006073451,0.0004574476,0.000220905,0.0002315517,0.0003818936,0.0004684598,0.0002010946,0.0004182419,0.000749415],"category_scores_gemma":[0.00008421082,0.0001463043,0.0003402141,0.0001451539,0.0002208619,0.0001926128,0.000391764,0.0004503782,0.000668351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004336479,"about_ca_system_score_gemma":0.0002178022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007671125,"about_ca_topic_score_gemma":0.0009301587,"domain_scores_codex":[0.9999181,0.000009438991,0.000005068195,0.00001770837,0.00002871665,0.00002091014],"domain_scores_gemma":[0.9999567,0.000004703109,0.00001109072,0.00000817315,0.000008904733,0.0000103762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004119939,0.000006003272,0.0002467227,0.00003326998,0.000004351151,0.0001098696,0.000007640348,0.00006090397,0.997924,0.0002327467,0.00005859435,0.001274661],"study_design_scores_gemma":[0.000007201474,0.00003281524,0.004407655,0.000006580295,0.00001093779,0.0006685623,0.00003834544,0.001372491,0.9845396,0.0001095282,0.008800938,0.000005531375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810356,0.004123732,0.01031234,0.0003181029,0.00007606229,0.00002607525,0.0005536104,0.0003103165,0.003244153],"genre_scores_gemma":[0.9892778,0.002074471,0.003042896,0.0000698908,0.00001037836,0.00002039443,0.0009417243,0.00004461278,0.004517811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007671125,"threshold_uncertainty_score":0.00314641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01196805425506261,"score_gpt":0.2361384438021422,"score_spread":0.2241703895470796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}