{"id":"W2108241808","doi":"10.1007/s00253-013-4898-6","title":"Construction and analysis of a genetically tuneable lytic phage display system","year":2013,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Canadian Institutes of Health Research","keywords":"Plasmid; Lytic cycle; Green fluorescent protein; Biology; Bacteriophage; Capsid; Escherichia coli; Fusion protein; Molecular biology; Expression vector; Suppressor; Genetics; Virus; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002780768,0.0002467652,0.000327964,0.0003343085,0.0002536874,0.0006798584,0.0003756026,0.0004397291,0.0008740012],"category_scores_gemma":[0.0003604519,0.0001575195,0.0002548202,0.0003127881,0.0002070416,0.0002034093,0.0003883705,0.0007263207,0.0007863685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004436898,"about_ca_system_score_gemma":0.0002347899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003765178,"about_ca_topic_score_gemma":0.0002534619,"domain_scores_codex":[0.9997254,0.00003724821,0.00002505969,0.00005470373,0.0001140971,0.00004351071],"domain_scores_gemma":[0.9998513,0.00002872544,0.00002645065,0.00002217563,0.00002734218,0.00004403016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001515143,0.00001956404,0.0000979491,0.00001601771,0.000002188014,0.0000295338,0.00001181896,0.00007464884,0.9987386,0.0001356389,0.00002180743,0.000837242],"study_design_scores_gemma":[0.00000666961,0.0001258719,0.001100245,0.000004103662,0.000007504961,0.0001320796,0.00001393902,0.002444995,0.9929588,0.00005157752,0.003148043,0.000006251522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.918977,0.0006980048,0.07583602,0.0001731027,0.0000552557,0.0003148126,0.001127132,0.0004679767,0.002350848],"genre_scores_gemma":[0.938576,0.0006108726,0.05205802,0.00008475316,0.00001327873,0.000269575,0.003255305,0.0001673789,0.004964611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008740012,"threshold_uncertainty_score":0.003219247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006292680015515835,"score_gpt":0.2270561600616418,"score_spread":0.220763480046126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}