{"id":"W2108317489","doi":"10.1017/s1355838202024056","title":"High-affinity hnRNP A1 binding sites and duplex-forming inverted repeats have similar effects on 5??? splice site selection in support of a common looping out and repression mechanism","year":2002,"lang":"en","type":"article","venue":"RNA","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Université de Sherbrooke","keywords":"splice; Binding site; Biology; Splice site mutation; RNA splicing; snRNP; Alternative splicing; Genetics; RNA; Molecular biology; Gene; Exon","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001763373,0.0002955032,0.0002527881,0.0001460629,0.0001537904,0.0003224058,0.0002996398,0.0003378628,0.001405075],"category_scores_gemma":[0.0001762692,0.0001910274,0.0003858085,0.0000560531,0.0003019028,0.0001209895,0.0002156548,0.0004644682,0.000252513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001988941,"about_ca_system_score_gemma":0.0001339355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005687036,"about_ca_topic_score_gemma":0.0006470276,"domain_scores_codex":[0.9998141,0.00004393221,0.00001641995,0.00003573377,0.00004669171,0.000043082],"domain_scores_gemma":[0.9997497,0.0000770371,0.00005742918,0.00003495542,0.00001432244,0.00006648611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001136841,0.00001665785,0.000180627,0.00001490507,0.0000039856,0.00002988464,0.000008526461,0.00008945421,0.9988443,0.00007854243,0.000007034407,0.0006123685],"study_design_scores_gemma":[0.00002656768,0.0004896969,0.007913867,0.000003523759,0.00001653962,0.0003154676,0.00002334042,0.001396203,0.9891543,0.00008224584,0.0005678065,0.0000105746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979429,0.0003507427,0.0009657971,0.00002282096,0.000006876774,0.000007465415,0.00004252909,0.00003491688,0.0006259402],"genre_scores_gemma":[0.9976636,0.0001220934,0.001271342,0.00003902624,0.000004328695,0.00001386256,0.0001155839,0.000008196508,0.0007619547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001405075,"threshold_uncertainty_score":0.004700482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02072259149434399,"score_gpt":0.2710413167389171,"score_spread":0.2503187252445731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}