{"id":"W2108330997","doi":"10.1186/1742-4690-9-s1-p9","title":"Three-dimensional modeling of DCIR and identification of new drugs blocking HIV-1 attachment and propagation","year":2012,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Human immunodeficiency virus (HIV); Blocking (statistics); Medicine; Virology; Receptor; Antibody; Bystander effect; Gp41; Immunology; Cell biology; Biology; Epitope; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001028375,0.0003104956,0.000281653,0.0001917618,0.000273194,0.0006782732,0.0004584151,0.0005902728,0.001670208],"category_scores_gemma":[0.0001470964,0.0002686616,0.0003651161,0.0002468798,0.0002809346,0.0003366269,0.0002278842,0.0003220445,0.0002867917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005187102,"about_ca_system_score_gemma":0.0005236564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004291163,"about_ca_topic_score_gemma":0.002944632,"domain_scores_codex":[0.9999439,0.00001167844,0.000002367881,0.000008301354,0.00002163625,0.00001209243],"domain_scores_gemma":[0.9999592,0.00001377216,0.000008849861,0.000005007339,0.000006962578,0.000006279652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00009623574,0.00007208934,0.0007881414,0.0001084508,0.00001939218,0.0001132508,0.00004770716,0.9483832,0.03280895,0.01117162,0.0007946854,0.00559625],"study_design_scores_gemma":[0.00001444411,0.00002438508,0.000169375,0.000005422351,0.000005643824,0.00001907931,0.00001287553,0.9911397,0.004704562,0.001126297,0.002769688,0.000008524034],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7142463,0.002799868,0.219058,0.001506625,0.0001978755,0.0001643884,0.002195169,0.0007129015,0.05911887],"genre_scores_gemma":[0.9368618,0.001936992,0.05500678,0.0001458292,0.00001858855,0.0001718627,0.0005758532,0.00008089001,0.005201442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004291163,"threshold_uncertainty_score":0.008532405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01996037240280016,"score_gpt":0.2707589176730081,"score_spread":0.250798545270208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}