{"id":"W2108330997","doi":"10.1186/1742-4690-9-s1-p9","title":"Three-dimensional modeling of DCIR and identification of new drugs blocking HIV-1 attachment and propagation","year":2012,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Human immunodeficiency virus (HIV); Blocking (statistics); Medicine; Virology; Receptor; Antibody; Bystander effect; Gp41; Immunology; Cell biology; Biology; Epitope; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000271187,0.00007772384,0.0001787144,0.0000913925,0.00005670124,0.000002159596,0.00004070254,0.0001172862,0.00004412068],"category_scores_gemma":[0.00003427138,0.00006562761,0.00002295392,0.00004391019,0.000140918,0.00006522754,0.00006181828,0.00009408408,0.00003075374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001800741,"about_ca_system_score_gemma":0.00003402196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001343628,"about_ca_topic_score_gemma":0.000009365735,"domain_scores_codex":[0.9992929,0.00006757434,0.0002475359,0.0001452295,0.00003958296,0.0002071771],"domain_scores_gemma":[0.9996349,0.00006117701,0.0001136496,0.0001175685,0.00003956562,0.00003311391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002914179,0.0002007409,0.2692758,0.00006125256,0.0002156378,6.716537e-7,0.0009968237,0.000141134,0.7123036,0.001276245,0.0002415141,0.0149951],"study_design_scores_gemma":[0.009118219,0.001905195,0.6138504,0.0001062486,0.0004135865,0.0002569198,0.0004115507,0.01298253,0.3571076,0.001954183,0.001396874,0.0004967772],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920699,0.00479104,0.00260172,0.0002250278,0.00007093008,0.0001735023,0.00001932683,0.000008762307,0.00003979205],"genre_scores_gemma":[0.9994566,0.0000610545,0.0002139817,0.00001136093,0.0000178859,0.000007393328,0.00008428848,0.000005487655,0.0001418806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3551961,"threshold_uncertainty_score":0.2676216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01996037240280016,"score_gpt":0.2707589176730081,"score_spread":0.250798545270208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}