{"id":"W2108358974","doi":"10.1111/j.1440-1681.2005.04149.x","title":"BLOCK OF Na<sup>+</sup> AND K<sup>+</sup> CURRENTS IN RAT VENTRICULAR MYOCYTES BY QUINACAINOL AND QUINIDINE","year":2005,"lang":"en","type":"article","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Quinidine; Sodium channel; Chemistry; Sodium; Electrophysiology; Potassium; Internal medicine; Patch clamp; Potassium channel; Voltage clamp; Myocyte; Biophysics; Pharmacology; Endocrinology; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001721508,0.0003374342,0.0002667631,0.0001057957,0.00008616188,0.0002563198,0.0004191238,0.0002142997,0.0007490891],"category_scores_gemma":[0.0002448682,0.0001163958,0.0001936641,0.00007695375,0.0002313301,0.0002732964,0.0001146056,0.0003016197,0.0002017767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001806341,"about_ca_system_score_gemma":0.0001567351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007909095,"about_ca_topic_score_gemma":0.0009724615,"domain_scores_codex":[0.9998876,0.00001468416,0.00002316852,0.00002125714,0.00002504598,0.00002832593],"domain_scores_gemma":[0.9998072,0.00004807807,0.00006793699,0.00001647126,0.00003722974,0.00002316763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002590193,0.00001446137,0.000252025,0.0001083862,0.000006998023,0.00006885157,0.00002694017,0.00006316789,0.9971675,0.00006094487,0.00002340609,0.001948224],"study_design_scores_gemma":[0.00005518471,0.001473625,0.01052037,0.00001317767,0.0000356161,0.0003023265,0.00004650631,0.0009816318,0.9851813,0.00004213509,0.001341084,0.000006974799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897211,0.00584351,0.002864029,0.00007036119,0.00003740227,0.00004576246,0.0002723058,0.0000888113,0.001056609],"genre_scores_gemma":[0.9950322,0.002103426,0.001889804,0.00004561918,0.00002228804,0.000048363,0.0002470943,0.00001165244,0.0005996146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007909095,"threshold_uncertainty_score":0.002505898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01778927377220756,"score_gpt":0.333300194238843,"score_spread":0.3155109204666354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}