{"id":"W2108375396","doi":"10.1161/atvbaha.111.230573","title":"RAGE-Dependent Activation of the Oncoprotein Pim1 Plays a Critical Role in Systemic Vascular Remodeling Processes","year":2011,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"NFAT; STAT3; Cancer research; Signal transduction; STAT protein; Small interfering RNA; Cell biology; Biology; Transcription factor; Chemistry; Transfection; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003817693,0.0001735,0.0004763314,0.00008475837,0.00008810696,0.00001117666,0.0001203368,0.0001791177,0.00007102026],"category_scores_gemma":[0.00008244409,0.0001198856,0.000149751,0.0001987302,0.0001244948,0.00008042668,0.00007150496,0.0001574674,0.000002229766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005062973,"about_ca_system_score_gemma":0.00008315382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006334626,"about_ca_topic_score_gemma":0.0001082552,"domain_scores_codex":[0.998732,0.0001303369,0.0003763703,0.0003613297,0.000151819,0.0002481081],"domain_scores_gemma":[0.9992994,0.00004086075,0.00009984003,0.0003822532,0.0001146513,0.00006297892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002428527,0.0002582852,0.02804706,0.0003118549,0.0001511451,6.552712e-8,0.002110467,0.000004885549,0.9667218,0.001508466,0.000002150776,0.000859559],"study_design_scores_gemma":[0.003452379,0.000996276,0.8750916,0.002077984,0.0002669389,0.000005744245,0.001715142,0.0007404772,0.1130077,0.002121659,0.0001594315,0.0003646778],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957643,0.0003911254,0.002900493,0.0001822107,0.00009416748,0.0005443686,0.000006173183,0.00002296626,0.00009424634],"genre_scores_gemma":[0.997218,0.001781474,0.0005911627,0.0002384243,0.00004893138,0.0000933932,0.000004254424,0.00002316331,0.000001237544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8537141,"threshold_uncertainty_score":0.4888792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04702396245170209,"score_gpt":0.2822463371705425,"score_spread":0.2352223747188404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}