{"id":"W2108422054","doi":"10.1128/iai.00263-08","title":"<i>Burkholderia pseudomallei</i> Type III Secretion System Mutants Exhibit Delayed Vacuolar Escape Phenotypes in RAW 264.7 Murine Macrophages","year":2008,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Burkholderia pseudomallei; Biology; Mutant; Secretion; Microbiology; Intracellular parasite; Wild type; Phenotype; Giant cell; Cell biology; Type three secretion system; Multinucleate; Intracellular; Gene; Bacteria; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001408181,0.0003228979,0.0002375349,0.0001052289,0.0001083362,0.0003009421,0.0001446832,0.0003202012,0.0004960489],"category_scores_gemma":[0.0001161129,0.0001272297,0.0002547207,0.00009468465,0.0001531846,0.0001458153,0.0001367429,0.0003764657,0.0004068728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002060781,"about_ca_system_score_gemma":0.0001163009,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00069766,"about_ca_topic_score_gemma":0.0007133751,"domain_scores_codex":[0.9998159,0.00003883421,0.0000257597,0.00002385193,0.00004599097,0.00004968889],"domain_scores_gemma":[0.9998357,0.00002459206,0.00006747229,0.00001832369,0.00001901409,0.00003478171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005555849,0.00001328371,0.0001603003,0.000008159793,0.000001738034,0.00003975103,0.000007606213,0.00001538669,0.9995459,0.00001596831,0.00001176598,0.0001245317],"study_design_scores_gemma":[0.00001319554,0.0005125601,0.009517656,0.000005749549,0.000008881974,0.0006055014,0.0000717979,0.0007461212,0.9877619,0.00003218171,0.000718331,0.000006284295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982336,0.0003404449,0.0007638797,0.00007031579,0.00001077177,0.00001053399,0.0002158813,0.00003448953,0.0003200717],"genre_scores_gemma":[0.9966428,0.0002261239,0.001441502,0.00006495664,0.000007102195,0.0000267595,0.0005114776,0.00001816706,0.001061026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00069766,"threshold_uncertainty_score":0.001659513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01891670158295406,"score_gpt":0.2481728098579705,"score_spread":0.2292561082750164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}