{"id":"W2108439538","doi":"10.1161/atvbaha.113.301533","title":"Impaired Coronary Collateral Growth in the Metabolic Syndrome Is in Part Mediated by Matrix Metalloproteinase 12–Dependent Production of Endostatin and Angiostatin","year":2013,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute","keywords":"Endostatin; Angiostatin; Matrix metalloproteinase; Metalloproteinase; Medicine; Internal medicine; Angiogenesis; Cardiology; Collateral circulation; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002320788,0.0006649919,0.0003229269,0.0003077621,0.0001114213,0.0001861452,0.00009411457,0.0002353731,0.001038998],"category_scores_gemma":[0.0002158389,0.000177109,0.0002820196,0.0001276479,0.0003613714,0.0001934615,0.0002153305,0.0004786546,0.0001194807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001675099,"about_ca_system_score_gemma":0.0001499452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003463862,"about_ca_topic_score_gemma":0.0005805317,"domain_scores_codex":[0.9998771,0.00002993743,0.0000112953,0.00002877839,0.00003315722,0.00001975333],"domain_scores_gemma":[0.9997213,0.0000292102,0.000135382,0.00002209743,0.00001750196,0.00007441578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009377271,0.00005863413,0.00499835,0.00004565216,0.00002107854,0.000283542,0.00001706857,0.00003031459,0.9917162,0.0000542409,0.00002499987,0.001812204],"study_design_scores_gemma":[0.0002148801,0.004670274,0.4010302,0.00003731682,0.0002001144,0.004411249,0.0001316402,0.00130663,0.586526,0.0001875603,0.001263487,0.00002062972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972193,0.0007598496,0.00158275,0.00005358181,0.000007364313,0.00001453687,0.00007909218,0.00003145499,0.0002521799],"genre_scores_gemma":[0.9975045,0.0006177134,0.001264942,0.00002343085,0.00001296505,0.00002517626,0.0001237983,0.000007817275,0.0004196643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001038998,"threshold_uncertainty_score":0.003475785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01507261236477728,"score_gpt":0.2481961046558589,"score_spread":0.2331234922910816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}