{"id":"W2108478641","doi":"10.1104/pp.109.151456","title":"Identification and Functional Characterization of Monofunctional<i>ent</i>-Copalyl Diphosphate and<i>ent</i>-Kaurene Synthases in White Spruce Reveal Different Patterns for Diterpene Synthase Evolution for Primary and Secondary Metabolism in Gymnosperms","year":2009,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Forest Service; Natural Sciences and Engineering Research Council of Canada; U.S. Forest Service; University of British Columbia; Natural Resources Canada; Genome British Columbia; Iowa State University; Genome Canada","keywords":"Diterpene; Physcomitrella patens; Biology; Biosynthesis; ATP synthase; Biochemistry; Secondary metabolism; Phosphofructokinase 2; Enzyme; Gene; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001328026,0.0001943232,0.0003091101,0.00008292728,0.00005538882,0.00001366962,0.0000573437,0.0001664427,0.000004147258],"category_scores_gemma":[0.00005252808,0.0001786365,0.00004706545,0.00004545995,0.0000614188,0.00002424144,0.00004021281,0.00006398644,1.02146e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001704171,"about_ca_system_score_gemma":0.00002593648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007335752,"about_ca_topic_score_gemma":0.00002642972,"domain_scores_codex":[0.9988528,0.00004613219,0.0003559887,0.0004779834,0.00006586473,0.0002011655],"domain_scores_gemma":[0.9995164,0.00007419183,0.0001881044,0.0001269532,0.00004345772,0.00005092081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001525545,0.0001691315,0.009013675,0.0002025508,0.00003018423,7.174205e-7,0.00001638577,0.000007015472,0.9872511,0.00006263726,0.0000431521,0.001677882],"study_design_scores_gemma":[0.0007638985,0.0001200057,0.6139342,0.00005076336,0.00002977825,0.00001691309,0.00001053528,0.0002459538,0.3844215,0.0001674315,0.000106999,0.0001320594],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942949,0.0007374987,0.001487253,0.0001723323,0.0001118244,0.0004172225,0.002769185,0.000006437316,0.000003320289],"genre_scores_gemma":[0.9918828,0.0007970022,0.00006129586,0.0001399336,0.000140931,0.00009647185,0.006826097,0.000009016638,0.0000464769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6049205,"threshold_uncertainty_score":0.7284585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006273586823076794,"score_gpt":0.1966666306772687,"score_spread":0.1903930438541919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}