{"id":"W2108530098","doi":"10.4161/cc.25509","title":"Metabolome and metaboproteome remodeling in nuclear reprogramming","year":2013,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Mayo Clinic","keywords":"Biology; Metabolome; Cell biology; Reprogramming; Induced pluripotent stem cell; Glycolysis; Biochemistry; Metabolomics; Embryonic stem cell; Metabolism; Cell; Bioinformatics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001264998,0.00008472661,0.0001111545,0.00003903962,0.00004097808,0.00002513266,0.00006575555,0.0001087139,0.0001336564],"category_scores_gemma":[0.00003030046,0.00008099001,0.00003420322,0.00006069453,0.00003344406,0.000005344477,0.00006845584,0.00008101063,0.00008022373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003023828,"about_ca_system_score_gemma":0.000007741588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008765003,"about_ca_topic_score_gemma":0.000009812591,"domain_scores_codex":[0.999306,0.00004640652,0.000140164,0.0002915958,0.00004255032,0.0001733276],"domain_scores_gemma":[0.9996594,0.000004464097,0.00003373752,0.0002165773,0.00002579656,0.00006002717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001494896,0.00002032957,0.000703051,0.000007429639,0.00000368974,0.000001465747,0.0000573604,0.00004643002,0.9940071,0.00005277731,0.0002144637,0.004870983],"study_design_scores_gemma":[0.0035534,0.0005763029,0.01187258,0.00002419055,0.00005759562,0.0001081607,0.001042054,0.0051637,0.5606715,0.002408774,0.4134229,0.001098843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946586,0.0009965721,0.0005947144,0.0001048581,0.0001485778,0.0001996516,8.424112e-7,0.00001450352,0.003281718],"genre_scores_gemma":[0.9900733,0.000162766,0.008326287,0.0002989678,0.0001260422,0.00002537254,0.000011787,0.00001790861,0.0009575502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4333356,"threshold_uncertainty_score":0.3302677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006497460472457779,"score_gpt":0.2049851056811561,"score_spread":0.1984876452086984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}