{"id":"W2108530098","doi":"10.4161/cc.25509","title":"Metabolome and metaboproteome remodeling in nuclear reprogramming","year":2013,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Mayo Clinic","keywords":"Biology; Metabolome; Cell biology; Reprogramming; Induced pluripotent stem cell; Glycolysis; Biochemistry; Metabolomics; Embryonic stem cell; Metabolism; Cell; Bioinformatics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002343,0.0003330752,0.0002289073,0.0003426599,0.0001781269,0.0005026112,0.0001505676,0.0002361662,0.00101156],"category_scores_gemma":[0.0002457867,0.0001294378,0.0002857154,0.0003319327,0.0002371721,0.0004808233,0.0004505792,0.0003153299,0.0003095327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003127037,"about_ca_system_score_gemma":0.00027618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002806147,"about_ca_topic_score_gemma":0.0004914213,"domain_scores_codex":[0.9998465,0.00002524605,0.000008757112,0.0000504734,0.00004741501,0.00002168171],"domain_scores_gemma":[0.999897,0.00001627417,0.00003533235,0.00001547862,0.00001814359,0.00001786705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001252163,0.00001225794,0.002580232,0.0000680692,0.00001252683,0.0001037144,0.00002864262,0.0002845789,0.9848368,0.0007289946,0.00005766626,0.01116127],"study_design_scores_gemma":[0.00001647631,0.000354215,0.1224882,0.00004524005,0.0000797264,0.001247883,0.000203862,0.004789146,0.8546188,0.003064286,0.01305963,0.00003255934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9548016,0.005353849,0.03205705,0.0003646863,0.00006556905,0.00006688295,0.002003901,0.0002652793,0.00502106],"genre_scores_gemma":[0.9853608,0.002724582,0.008190644,0.0001503746,0.00001929455,0.00005782712,0.001640509,0.00003207123,0.001823902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00101156,"threshold_uncertainty_score":0.003383994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006497460472457779,"score_gpt":0.2049851056811561,"score_spread":0.1984876452086984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}