{"id":"W2108572537","doi":"10.1002/ijc.10647","title":"Antiproliferative, antiangiogenic and proapoptotic activity of h‐R3: A humanized anti‐EGFR antibody","year":2002,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto; McMaster University","funders":"","keywords":"Cancer research; In vivo; Oncogene; A431 cells; Apoptosis; Epidermal growth factor receptor; Monoclonal antibody; Epidermal growth factor; Cell culture; In vitro; Cytotoxic T cell; Cell growth; Antibody; Biology; Cell cycle; Cancer; Immunology; Medicine; Receptor; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003236562,0.0001379611,0.0004431235,0.000373473,0.00003518427,0.00003966151,0.000244227,0.00007034986,0.001358223],"category_scores_gemma":[0.0001653434,0.0001112813,0.0001735368,0.0001903916,0.0001812502,0.0002400127,0.00006649844,0.0003297803,0.00000744864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001941131,"about_ca_system_score_gemma":0.0002321046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008911997,"about_ca_topic_score_gemma":0.00001556258,"domain_scores_codex":[0.9980242,0.00006894255,0.0004638843,0.000170285,0.001070407,0.000202275],"domain_scores_gemma":[0.9980478,0.00007474364,0.0004073338,0.0001337265,0.001191934,0.0001444387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001364091,0.0007409747,0.3480168,0.0002292432,0.002182246,0.0004647039,0.0009007434,0.00003423333,0.5812038,0.0002652066,0.003290172,0.06130781],"study_design_scores_gemma":[0.01372829,0.001676331,0.6541964,0.002462809,0.0005005196,0.001914417,0.0001315723,0.004132475,0.3034601,0.0002701408,0.01709167,0.0004353332],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893345,0.004990777,0.0003270782,0.003484544,0.0005532256,0.0002210411,0.0000263779,0.000008443729,0.001054023],"genre_scores_gemma":[0.9938309,0.004567231,0.0003874984,0.0001726955,0.0006305036,0.000005113383,0.000001735614,0.00002245775,0.000381818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3061796,"threshold_uncertainty_score":0.9995547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05122474526373232,"score_gpt":0.4222190801524165,"score_spread":0.3709943348886842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}