{"id":"W2108582952","doi":"10.1034/j.1600-0749.13.s8.20.x","title":"Intracellular Vesicular Trafficking of Tyrosinase Gene Family Protein in Eu‐ and Pheomelanosome Biogenesis","year":2000,"lang":"en","type":"article","venue":"Pigment Cell Research","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Melanosome; Tyrosinase; Cell biology; Endosome; Endoplasmic reticulum; Golgi apparatus; Transport protein; Vesicular transport protein; Biology; Vesicle; ER retention; Melanin; Intracellular; Chemistry; Biochemistry; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001205191,0.0004590244,0.0004289757,0.0005489829,0.0002069187,0.0004689691,0.0002670863,0.0004183683,0.001113185],"category_scores_gemma":[0.00008212605,0.00009170949,0.0002560328,0.0005266026,0.0001805215,0.0005580101,0.0003327178,0.0004510558,0.000915999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005061694,"about_ca_system_score_gemma":0.0002180332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003787327,"about_ca_topic_score_gemma":0.0005083416,"domain_scores_codex":[0.9999315,0.0000100973,0.000008949023,0.00001975113,0.00001470728,0.000015148],"domain_scores_gemma":[0.9999597,0.000006611488,0.00001179313,0.00000175137,0.00001263109,0.000007519735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004378951,0.0001614593,0.001732086,0.009467212,0.00009912558,0.003785828,0.0002619331,0.001258615,0.5260044,0.01298539,0.02377611,0.42003],"study_design_scores_gemma":[0.00001855704,0.0004701362,0.01278684,0.0007497474,0.0001431243,0.008684778,0.000179672,0.0007774875,0.07292706,0.002437858,0.9007801,0.00004475322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.02031532,0.9671674,0.003070862,0.0004800209,0.00114542,0.00003528146,0.0001306084,0.00005253204,0.007602512],"genre_scores_gemma":[0.1010901,0.8738936,0.003397524,0.0005035876,0.001129088,0.00005998184,0.0006218657,0.00002666264,0.01927753],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001113185,"threshold_uncertainty_score":0.003723919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0260284942244764,"score_gpt":0.2940971754167097,"score_spread":0.2680686811922333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}