{"id":"W2108582952","doi":"10.1034/j.1600-0749.13.s8.20.x","title":"Intracellular Vesicular Trafficking of Tyrosinase Gene Family Protein in Eu‐ and Pheomelanosome Biogenesis","year":2000,"lang":"en","type":"article","venue":"Pigment Cell Research","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Melanosome; Tyrosinase; Cell biology; Endosome; Endoplasmic reticulum; Golgi apparatus; Transport protein; Vesicular transport protein; Biology; Vesicle; ER retention; Melanin; Intracellular; Chemistry; Biochemistry; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007830769,0.0001232252,0.0001459167,0.0001437076,0.00007016173,0.00002627749,0.0001506618,0.0001207921,0.0001175953],"category_scores_gemma":[0.00001540742,0.0001215454,0.00004030754,0.0002321321,0.0001141784,0.000005400739,0.00006577398,0.0001107579,0.00001890086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000277487,"about_ca_system_score_gemma":0.00006117966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009258775,"about_ca_topic_score_gemma":0.000009448403,"domain_scores_codex":[0.9983994,0.0002435223,0.0002676267,0.0003743559,0.0003670336,0.000348087],"domain_scores_gemma":[0.9995268,0.00001895114,0.0000367576,0.0002618629,0.00006272677,0.00009289211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001397513,0.000196953,0.0008973567,0.00007416234,0.00001144598,0.00001975261,0.0001241752,0.0000820651,0.9867332,0.0000318416,0.0001185784,0.01157073],"study_design_scores_gemma":[0.0007885681,0.0003961967,0.002328296,0.00003014673,0.000005045233,0.000002543663,0.0001424179,0.0002379685,0.9935059,0.00002928378,0.002407574,0.0001260501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949034,0.0031459,0.00008343525,0.00005317212,0.0000208108,0.0005199834,0.00001104934,0.00000476534,0.001257519],"genre_scores_gemma":[0.9964401,0.001642943,0.0008603243,0.00002408436,0.00008092136,0.00006578171,0.00008978326,0.000020364,0.0007757046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01144468,"threshold_uncertainty_score":0.4956478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0260284942244764,"score_gpt":0.2940971754167097,"score_spread":0.2680686811922333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}