{"id":"W2108585052","doi":"10.1200/jco.2006.06.1440","title":"Phase III Trial Comparing 4-Day Chronomodulated Therapy Versus 2-Day Conventional Delivery of Fluorouracil, Leucovorin, and Oxaliplatin As First-Line Chemotherapy of Metastatic Colorectal Cancer: The European Organisation for Research and Treatment of Cancer Chronotherapy Group","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":227,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre","funders":"","keywords":"Oxaliplatin; Medicine; Fluorouracil; Colorectal cancer; Internal medicine; Oncology; Chemotherapy; Phases of clinical research; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002511861,0.000163682,0.001392841,0.0001038121,0.0001090786,0.000006899601,0.00007734802,0.0000853267,0.0001069034],"category_scores_gemma":[0.0001307212,0.00009764225,0.0002571015,0.0001152128,0.0005932489,0.00005913612,0.00002058355,0.0001736819,1.650403e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003255648,"about_ca_system_score_gemma":0.0006825096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001860218,"about_ca_topic_score_gemma":0.002015055,"domain_scores_codex":[0.9971554,0.0005260746,0.001638445,0.0001942487,0.0003086606,0.0001771262],"domain_scores_gemma":[0.9945542,0.003246876,0.001466155,0.00009606364,0.0005553843,0.00008136354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4183602,0.008713089,0.01958424,0.00005506298,0.004081517,0.00001716658,0.001121304,0.00008892828,0.006994679,0.0001211376,0.0001903655,0.5406723],"study_design_scores_gemma":[0.6070731,0.202381,0.1677423,0.0001403295,0.00082755,0.00001571661,0.0003807273,0.0009335744,0.01013663,0.0003029092,0.009931711,0.0001344671],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891604,0.007608681,0.00007512115,0.001382112,0.0004581997,0.001131364,0.00003535559,0.000003470824,0.0001452776],"genre_scores_gemma":[0.9759666,0.02287824,0.0002689778,0.00003077994,0.0007275298,0.00004904692,0.00001252066,0.00001906807,0.00004718665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5405378,"threshold_uncertainty_score":0.3981735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2516237123749373,"score_gpt":0.5059338816823887,"score_spread":0.2543101693074514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}