{"id":"W2108585052","doi":"10.1200/jco.2006.06.1440","title":"Phase III Trial Comparing 4-Day Chronomodulated Therapy Versus 2-Day Conventional Delivery of Fluorouracil, Leucovorin, and Oxaliplatin As First-Line Chemotherapy of Metastatic Colorectal Cancer: The European Organisation for Research and Treatment of Cancer Chronotherapy Group","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":227,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre","funders":"","keywords":"Oxaliplatin; Medicine; Fluorouracil; Colorectal cancer; Internal medicine; Oncology; Chemotherapy; Phases of clinical research; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002606837,0.001057255,0.001761284,0.0003365756,0.0003047728,0.0007079054,0.0007805902,0.001261849,0.004008541],"category_scores_gemma":[0.001827447,0.0003773005,0.001763222,0.0003217164,0.0007763059,0.0005198803,0.0003439609,0.001658586,0.0003904036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008449045,"about_ca_system_score_gemma":0.001366696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000681547,"about_ca_topic_score_gemma":0.001162582,"domain_scores_codex":[0.9991511,0.0005873982,0.00003507878,0.0001080117,0.00003949682,0.00007883841],"domain_scores_gemma":[0.9987695,0.0003946666,0.0003735221,0.0001003124,0.00005346128,0.0003085499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9784234,0.006615679,0.0008435682,0.0002208832,0.0006463234,0.00002076447,0.00002528843,0.0005542138,0.002360036,0.00007798632,0.0003392526,0.009872592],"study_design_scores_gemma":[0.8871003,0.1093022,0.001930331,0.00001652148,0.0003075002,0.00002186895,0.000007690882,0.0004476778,0.0004913305,0.00006297126,0.0003040931,0.00000749825],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943643,0.001703662,0.0005158764,0.0003112636,0.0002708742,0.001771066,0.0003505864,0.00003879821,0.0006735509],"genre_scores_gemma":[0.9905437,0.00100975,0.0020265,0.0007045611,0.0003277648,0.003184527,0.000791713,0.00001610456,0.001395335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004008541,"threshold_uncertainty_score":0.01378644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2516237123749373,"score_gpt":0.5059338816823887,"score_spread":0.2543101693074514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}