{"id":"W2108611713","doi":"10.1371/journal.pone.0019421","title":"Bacterial Transmembrane Proteins that Lack N-Terminal Signal Sequences","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Streptomyces coelicolor; Membrane protein; Biology; Transmembrane protein; Translocon; Cell biology; Vesicle-associated membrane protein 8; Signal peptide; Biochemistry; Bacterial outer membrane; Transmembrane domain; Peripheral membrane protein; Integral membrane protein; Bacteria; Peptide sequence; Membrane; Genetics; Streptomyces; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008913098,0.0003452966,0.0002235481,0.000155689,0.0002065428,0.0002970661,0.0001121453,0.0003325472,0.0006957494],"category_scores_gemma":[0.0002115825,0.0001023047,0.0001658907,0.0002740225,0.0002735474,0.0002065499,0.0002742922,0.0003200843,0.0007750412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002173098,"about_ca_system_score_gemma":0.0002521644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003296008,"about_ca_topic_score_gemma":0.0004083081,"domain_scores_codex":[0.9998703,0.00001508979,0.00001071963,0.00002148996,0.00005389842,0.00002848923],"domain_scores_gemma":[0.9998569,0.00001861724,0.0000537589,0.00001704047,0.00001731613,0.00003632559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009811336,0.00000981442,0.0007331055,0.00004641332,0.000005450968,0.0001322536,0.00001037628,0.00003458044,0.9960372,0.0002456253,0.00005907158,0.002588134],"study_design_scores_gemma":[0.0000224674,0.0002873633,0.02484562,0.00001766071,0.00004944235,0.003222934,0.00008996588,0.001051602,0.950021,0.0005060106,0.01987389,0.00001210102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871823,0.002758986,0.006845971,0.0001899625,0.00005023516,0.00002400805,0.0007357621,0.0001923066,0.002020481],"genre_scores_gemma":[0.9857715,0.00154358,0.007837175,0.00009508737,0.00001264109,0.00001743322,0.002047603,0.00002847264,0.002646492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006957494,"threshold_uncertainty_score":0.002327442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06385505304789497,"score_gpt":0.2258259784658264,"score_spread":0.1619709254179315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}