{"id":"W2108626100","doi":"10.1016/s0022-1759(00)00306-9","title":"Comparison of chemiluminescent assays and colorimetric ELISAs for quantification of murine IL-12, human IL-4 and murine IL-4: chemiluminescent substrates provide markedly enhanced sensitivity","year":2001,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Manitoba Health Research Council","keywords":"Chemiluminescence; Chemistry; Cytokine; Assay sensitivity; Sensitivity (control systems); Immunology; Molecular biology; Biology; Chromatography; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003709883,0.0003748976,0.001493893,0.0003827446,0.0001946662,0.00002203775,0.000266214,0.0004752786,0.00007320577],"category_scores_gemma":[0.002348201,0.000287101,0.0002840809,0.000378658,0.0008488813,0.0001706288,0.0001265582,0.000576443,9.937876e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006883538,"about_ca_system_score_gemma":0.0000771124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003947411,"about_ca_topic_score_gemma":0.00000295895,"domain_scores_codex":[0.9961145,0.00127423,0.001719517,0.0003532014,0.0001115737,0.0004269634],"domain_scores_gemma":[0.9946048,0.002483313,0.001851299,0.0003435044,0.0006738536,0.00004322884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00703822,0.001081482,0.004408635,0.0001687411,0.0004933203,0.000004368543,0.0002871809,0.000003132353,0.9423366,0.0001197114,0.00006536923,0.04399323],"study_design_scores_gemma":[0.003439853,0.002644079,0.08805828,0.00019106,0.0001852842,0.0002656979,0.0007143026,0.00001823063,0.9003797,0.00009812125,0.003750883,0.0002544982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9682046,0.02156385,0.009015174,0.0001868767,0.0003599797,0.0005393777,0.000032326,0.00002120179,0.00007661431],"genre_scores_gemma":[0.9799366,0.004032951,0.01565262,0.00002560043,0.00004164577,0.00001752102,0.00002729306,0.00002392029,0.0002418207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08364964,"threshold_uncertainty_score":0.9999581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06217966974828435,"score_gpt":0.3841603568290911,"score_spread":0.3219806870808067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}